Protein Alignment mle and Rhau

DIOPT Version :10

• Sequence 1: NP_476641.1
• Gene: mle / 35523
• FlyBaseID: FBgn0002774
• Length: 1293
• Species: Drosophila melanogaster
• Sequence 2: NP_610056.1
• Gene: Rhau / 35339
• FlyBaseID: FBgn0032883
• Length: 942
• Species: Drosophila melanogaster
• Alignment Length: 977
• Identity: 303/977 - (31%)
• Similarity: 482/977 - (49%)
• Gaps: 116/977 - (11%)

  Fly   203 ELSIYVPALNRTVTARESGSNKKSASKSCALSLVRQLFHLNVIEPFSGTLKKKKDEQLKPYPVKL 267
            ::.:|...|.|. ..::.|.|.:|......|.       .||..| ||.|::.| |.::.|  ..
  Fly    25 DIGLYYRNLARQ-QKKDRGENAESKEPQIRLG-------CNVSAP-SGVLERVK-ELMEDY--SR 77

  Fly   268 SPNLINKIDEVIKGLDLPVVNPRNIKIELDGPPIPLIVNLSRIDSSQQDGEKRQESSVIPWAPPQ 332
            :|:..|             |:.:|:..:..    ....:|..::..:...|.::.::.:.|..|:
  Fly    78 APSRQN-------------VDDKNVDAKFQ----QQFRHLLSVNFEEFVAETKERNADLDWVNPK 125

  Fly   333 ANWNTWHACNIDEGELATTSIDDLSMDYERSLRDRRQNDNEYRQFLEFREKLPIAAMRSEILTAI 397
                      :||         .|.::.     .:||.:...::.||.|:|||......:|:.|:
  Fly   126 ----------LDE---------RLQLEL-----GQRQLEENAKKRLEARKKLPTMKYADDIIQAV 166

  Fly   398 NDNPVVIIRGNTGCGKTTQIAQYILDDYICSGQGGYANIYVTQPRRISAISVAERVARERCEQLG 462
            .:|.|::|.|:||||||||:.|.:|||.|..|......|..|||||||||::||.|:.||||.||
  Fly   167 RENQVILIVGSTGCGKTTQVPQILLDDAISRGCASSCRIICTQPRRISAIAIAEWVSYERCESLG 231

  Fly   463 DTVGYSVRFESVFPRPYGAILFCTVGVLLRKLEAG--LRGVSHIIVDEIHERDVNSDFLLVILRD 525
            ::|||.:|.||...|...:|.:||.||||::|::.  :..:|.:|:||||||.|.:|.|:.:|:.
  Fly   232 NSVGYQIRLESRKARERASITYCTTGVLLQQLQSDPLMHNLSVLILDEIHERSVETDLLMGLLKV 296

  Fly   526 MVDTYPDLHVILMSATIDTTKFSKYFGICPVLEVPGRAFPVQQFFLEDIIQMTDFVPSAESRRKR 590
            ::...|||.|||||||:....|..||..||:..:.|..|||:..:|||::..|::.......|:.
  Fly   297 ILPHRPDLKVILMSATVREQDFCDYFNNCPMFRIEGVMFPVKMLYLEDVLSKTNYEFQKFRDRRP 361

  Fly   591 KEVEDEEQLLSEDKDEAEIN-YNKVCEDKYSQKTRNAMAM-LSESDVSFELLEALLMHIKSKNIP 653
            |....|.::    |.||.|. |.:...:.|..:..:.:.: .||.....:.:..|:.:|......
  Fly   362 KRDPPERRM----KHEAMIEPYLRRIRNSYDSRVLDKLRLPESEGCEDIDFIADLVYYICENEPE 422

  Fly   654 GAILVFLPGWNLIFALMKFLQNTNIFGDTSQYQ-------ILPCHSQIPRDEQRKVFEPVPEGVT 711
            |||||||||::.|..|...|....    ||:.|       :.|.||.:...||:.||...|.|..
  Fly   423 GAILVFLPGYDKISQLYNILDKPK----TSKGQRWRDHMAVFPLHSLMQSGEQQAVFRRPPAGQR 483

  Fly   712 KIILSTNIAETSITIDDIVFVIDICKARMKLFTSHNNLTSYATVWASKTNLEQRKGRAGRVRPGF 776
            |:|:||.|||||:||||:|:||:..:.:...:....|:.|...||.:|.|.:||:|||||||||.
  Fly   484 KVIISTIIAETSVTIDDVVYVINSGRTKATNYDIETNIQSLDEVWVTKANTQQRRGRAGRVRPGI 548

  Fly   777 CFTLCSRARFQALEDNLTPEMFRTPLHEMALTIKLLRLGSIHHFLSKALEPPPVDAVIEAEVLLR 841
            |:.|.||||...::|..|||:.|:.|..:.|::|||.:...:.||...:..|..:|:.....||:
  Fly   549 CYNLFSRAREDRMDDIPTPEILRSKLESIILSLKLLHIDDPYRFLQTLINAPNPEAIKMGVELLK 613

  Fly   842 EMRCLDANDELTPLGRLLARLPIEPRLGKMMVLGAVFGCADLMAIMASYSSTFSEVFS------- 899
            .:..||....|||||..||:|||:|::|||:::.|:|.|.|.:...|:..|..|..:|
  Fly   614 RIEALDQTGTLTPLGMHLAKLPIDPQMGKMILMSALFCCLDPITSAAAALSFKSPFYSPLGKESR 678

  Fly   900 LDIGQRRLANHQKALSGTKCSDHVAMIVASQMWRREKQRGEHMEARFCDWKGLQMSTMNVIWDAK 964
            :|..:||:|.:.:       |||  ::|.:.:......|..|.|..||....|...|:..:...|
  Fly   679 VDEIKRRMARNMR-------SDH--LMVHNTIIAYRDSRYSHAERDFCYKNFLSSMTLQQLERMK 734

  Fly   965 QQLLDLLQQAGF--PEEC--MISHEVDERIDGDDPVLDVSLALLCLGLYPNICVHKEKRKV---- 1021
            .|..:||....|  ...|  ..|::..|:|    |:|   .|::..|||||:...::.|::
  Fly   735 NQFSELLYNYKFLASSNCKDAASNKNSEKI----PLL---RAIIGAGLYPNMAHLRKSRQIKNRV 792

  Fly  1022 ------LTTESKAALLHKTSVNCSNLAVTFPYPFFVFGEKIRTRAVSCKQLSMVSPLQVILFGSR 1080
                  .|.:.:....|.:|||.....  |...:||:.::.::..:.....:||.|:.:|:||..
  Fly   793 RAIHTMATDDGRRVNFHPSSVNSGESG--FDSAYFVYFQRQKSTDLFLLDSTMVFPMALIIFGDG 855

  Fly  1081 -KIDLAANN-IVRVDNWLNFDIEPELAAKIGALKPALEDLITVACDNPSDILRLEEPY-AQLVKV 1142
             :..:..|. .:.|.....|....|.|..:..|:..||.|:......|:.|  .|..| .||:|.
  Fly   856 VEAGVTQNTPYLCVAKTYYFKCNRETADVVIQLRSNLEKLLLKKALYPAPI--EENGYEKQLIKA 918

  Fly  1143 VK 1144
            ::
  Fly   919 IE 920

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mle	NP_476641.1	DSRM_DHX9_rpt1	2..70	CDD:380683
		DSRM_DHX9_rpt2	167..241	CDD:380684	7/37 (19%)
		DEXHc_DHX9	326..559	CDD:350730	94/234 (40%)
		HrpA	378..>889	CDD:441249	207/521 (40%)
		OB_NTP_bind	1002..1079	CDD:400182	20/86 (23%)
Rhau	NP_610056.1	HrpA	160..>664	CDD:441249	202/511 (40%)
		OB_NTP_bind	767..856	CDD:400182	22/93 (24%)