Sequence 1: | NP_476641.1 | Gene: | mle / 35523 | FlyBaseID: | FBgn0002774 | Length: | 1293 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_848144.3 | Gene: | Dhx33 / 216877 | MGIID: | 2445102 | Length: | 698 | Species: | Mus musculus |
Alignment Length: | 708 | Identity: | 208/708 - (29%) |
---|---|---|---|
Similarity: | 330/708 - (46%) | Gaps: | 117/708 - (16%) |
- Green bases have known domain annotations that are detailed below.
Fly 367 RRQ-------NDNEYRQFLEF-REKLPIAAMRSEILTAIN--DNPVVIIRGNTGCGKTTQIAQYI 421
Fly 422 LDDYICSGQGGYANIYVTQPRRISAISVAERVARERCEQLGDTVGYSVRFESVFPRPYGAILFCT 486
Fly 487 VGVLLRKL--EAGLRGVSHIIVDEIHERDVNSDFLLVIL------RDMVDTYPDLHVILMSATID 543
Fly 544 TTKFSKYFGICPVLEVPGRAFPVQQFFLEDIIQMTDFVPSAESRRKRKEVEDEEQLLSEDKDEAE 608
Fly 609 INYNKVCEDKYSQKTRNAMAMLSESDVSFELLEALLMHIKSKNIPGA--ILVFLPGWNLIFALMK 671
Fly 672 FLQN--TNIFGDTSQYQILPCHSQIPRDEQRKVFEPVPEGVTKIILSTNIAETSITIDDIVFVID 734
Fly 735 ICKARMKLFTSHNNLTSYATVWASKTNLEQRKGRAGRVRPGFCFTLCSRARFQALEDNLTPEMFR 799
Fly 800 TPLHEMALTIKLLRLGSI--HHFLSKALEPPPVDAVIEAEVLLREMRCLDANDELTPLGRLLARL 862
Fly 863 PIEPRLGKMMVLGAVFGCADLMAIMASYSSTFSEVFSLDIGQRRLANHQKALSGTKCSDHVAMIV 927
Fly 928 ASQMWRREKQRGEHMEARFCDWKGLQMSTMNVIWDAKQQLLDLLQQAGFPEECMISHEVDERIDG 992
Fly 993 DDPVLDVSLALLCL--GLYPNICVHKEKRKVLTTES-KAALLHKTSV--NCSNLAVTF 1045 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
mle | NP_476641.1 | DSRM | 4..68 | CDD:214634 | |
DSRM | 170..240 | CDD:214634 | |||
DEXDc | 393..569 | CDD:214692 | 83/185 (45%) | ||
DEXDc | 402..542 | CDD:238005 | 67/147 (46%) | ||
ATP-synt_B | <584..644 | CDD:304375 | 2/59 (3%) | ||
Helicase_C | 643..772 | CDD:278689 | 47/132 (36%) | ||
HA2 | 842..926 | CDD:214852 | 21/83 (25%) | ||
OB_NTP_bind | 974..1078 | CDD:285018 | 14/77 (18%) | ||
Dhx33 | NP_848144.3 | Required for nucleolar location. /evidence=ECO:0000250|UniProtKB:Q9H6R0 | 1..71 | 11/30 (37%) | |
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..20 | ||||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 29..50 | 3/9 (33%) | |||
DEXDc | 49..252 | CDD:214692 | 92/210 (44%) | ||
DEXDc | 83..225 | CDD:238005 | 68/149 (46%) | ||
DEAH box | 185..188 | 2/2 (100%) | |||
Helicase_C | 282..399 | CDD:278689 | 44/116 (38%) | ||
IBP39 | 409..>500 | CDD:288304 | 26/91 (29%) | ||
HA2, required for interaction with EIF3G and RPL26. /evidence=ECO:0000250|UniProtKB:Q9H6R0 | 462..553 | 24/91 (26%) | |||
HA2 | 469..554 | CDD:214852 | 22/85 (26%) | ||
Critical for rDNA-binding | 536..550 | 1/14 (7%) | |||
OB_NTP_bind | 588..688 | CDD:285018 | 16/86 (19%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG1643 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |