Protein Alignment mle and LOC1271086

DIOPT Version :10

• Sequence 1: NP_476641.1
• Gene: mle / 35523
• FlyBaseID: FBgn0002774
• Length: 1293
• Species: Drosophila melanogaster
• Sequence 2: XP_309832.5
• Gene: LOC1271086 / 1271086
• VectorBaseID: AGAMI1_013055
• Length: 688
• Species: Anopheles gambiae
• Alignment Length: 801
• Identity: 216/801 - (26%)
• Similarity: 330/801 - (41%)
• Gaps: 188/801 - (23%)

  Fly   354 DDLSMDYERSLRDRRQNDNEYRQFL----------EFREKLPIAAMRSEILTAINDNPVVIIRGN 408
            ||.|...|   ||....|:....|:          ..||:|||...|.:||..:.....:::.|.
Mosquito    13 DDESFASE---RDAAPADDHVTSFVFNAHQSLNLAAQRERLPIRQYRDQILYCLEHYQTLVLVGE 74

  Fly   409 TGCGKTTQIAQYILDDYICSGQGGYANIYVTQPRRISAISVAERVARERCEQLGDTVGYSVRFES 473
            ||.||:||:.||:.:    .|......|.:|:|||||||::|:|||.||.|..|:|||.|:||.|
Mosquito    75 TGSGKSTQVPQYLYE----FGWHTKGLIGITEPRRISAITLADRVATERGELCGETVGVSIRFIS 135

  Fly   474 VFPRPYGAILFCTVGVLLRKLEAG--LRGVSHIIVDEIHERDVNSDFLLVILRDMVDTYPDLHVI 536
            ........|.:.|.|:|||::.|.  |...:.|:|||.|||:..:|..|.:|:.:....|:|.:|
Mosquito   136 KCDPAQTKIKYMTEGILLREMLADPLLTQYAVIMVDEAHERNTLTDTALGLLKKIARKRPNLRII 200

  Fly   537 LMSATIDTTKFSKYFGI---------CPVLEVPGRAFPVQQFFLEDIIQMTDFVPSAESRRKRKE 592
            :.|||:|...|..:|.:         ..:|.|.||.:..:.::|.|
Mosquito   201 ISSATVDAELFRDFFNLKSKGAAKDTAVILTVEGRMYAQEIYYLRD------------------- 246

  Fly   593 VEDEEQLLSEDKDEAEINYNKVCEDKYSQKTRNAMAMLSESDVSFELLEALLMHIKSKNIPGAIL 657
                                 .|.| |.::|.|.                 :|.|......|.:|
Mosquito   247 ---------------------PCPD-YVKETVNT-----------------VMKIHRAEGKGDVL 272

  Fly   658 VFLPGWNLIFALMKFLQNTNIFGDTSQYQILPCHSQIPRDEQRKVFEPVPEGVTKIILSTNIAET 722
            .||.|...:...:..|:...........||||.:..:...:|.|||...|:||.|::|:||||||
Mosquito   273 AFLTGQEEVLRAVDLLREHVEASGKEDMQILPMYGTLSNADQLKVFFTAPKGVRKVVLATNIAET 337

  Fly   723 SITIDDIVFVIDICKARMKLFTSHNNLTSYATVWASKTNLEQRKGRAGRVRPGFCFTLCSRARFQ 787
            |:||..||:|||....::|.:::.:...|...|..||...|||.|||||:|.|..:.|.:...::
Mosquito   338 SVTIPGIVYVIDCGFVKLKWYSADSTTDSLVVVPVSKAAAEQRAGRAGRIRSGKVYRLYTEEAWE 402

  Fly   788 ALEDNLTPEMFRTPLHEMALTIKLLRLGSIHHFLSKALEPPPVDAVIEAEVLLREMRCLDANDEL 852
            .|.::..|||.|:.|....|.:|.|.:.:|..|...:  |||...::.....|..:..|||..:|
Mosquito   403 KLPEHTPPEMRRSDLCSTVLFLKALGIDNILRFTFPS--PPPAKNLLACLETLYALEALDAEGQL 465

  Fly   853 T-PLGRLLARLPIEPRLGKMMVLGAVFGCAD---LMAIMASYSSTFSEVFSLDIGQRRLANHQKA 913
            | |:|..||.:.|.|.:.||:......||::   ::..|....|.||          :.|..|.|
Mosquito   466 TSPVGYFLAEMSIPPMMAKMLYKAGEMGCSEEILIIIAMLQVQSVFS----------KPAGGQAA 520

  Fly   914 LSG--TKCSDHVA---MIVASQMWRREKQRGEHMEARFCDWKGLQMSTMNVIWDAKQQLLDLLQQ 973
            :.|  .|.:..||   :|....::....:.|.  ..:||....|....:....:.|.||..:|::
Mosquito   521 IRGRIAKRNFEVAEGDLITLLNVYCAFVESGR--TKKFCGRNFLIYRNLKRAHEIKTQLAGMLER 583

  Fly   974 AGFPEECMISHEVDERIDGDDPVL----DVSLALLCL--GLYPNICVHKEKRKVLTTESKAALLH 1032
                 |..|            |:|    :|.....|:  |.:|                .||.||
Mosquito   584 -----ELNI------------PLLSAGGNVETICRCIVAGFFP----------------YAAYLH 615

  Fly  1033 ------------KTSVNCSNLAVTFPYP-FFVFGEKIRTRAVSCKQLSMVSPLQVILFGSRKIDL 1084
                        :.|::..:...|...| :.||.|.|.|..:..|.|:::.
Mosquito   616 HSGVYRTVRGNTELSIHPLSALYTEQQPQWVVFCELIHTTKLFMKDLTVIQ-------------- 666

  Fly  1085 AANNIVRVDNWLNFDIEPELA 1105
                    ..||     ||:|
Mosquito   667 --------QQWL-----PEIA 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mle	NP_476641.1	DSRM_DHX9_rpt1	2..70	CDD:380683
		DSRM_DHX9_rpt2	167..241	CDD:380684
		DEXHc_DHX9	326..559	CDD:350730	78/225 (35%)
		HrpA	378..>889	CDD:441249	162/535 (30%)
		OB_NTP_bind	1002..1079	CDD:400182	17/91 (19%)
LOC1271086	XP_309832.5	None