DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BubR1 and AT5G05510

DIOPT Version :9

Sequence 1:	NP_477382.1	Gene:	BubR1 / 35522	FlyBaseID:	FBgn0263855	Length:	1460	Species:	Drosophila melanogaster
Sequence 2:	NP_196170.1	Gene:	AT5G05510 / 830434	AraportID:	AT5G05510	Length:	471	Species:	Arabidopsis thaliana

Alignment Length:	516	Identity:	106/516 - (20%)
Similarity:	194/516 - (37%)	Gaps:	134/516 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 EVRTYKGADPLGAWYTFICWIEQSYPAGGSGSGLQTVLHQCLTKFEDDERYRQDKRLIKLFIKFM 110
            ::::|.|.|.|..|...:..:::|.|:......|...|.:|...||.|:||:.|.|.|:::::.|
plant    18 DIKSYSGKDHLLPWIRGVKKMKESLPSQILNEKLPRFLQKCAESFESDKRYKNDSRYIRVWLQLM 82

  Fly   111 EKQKDKIEFYQQMYNNGIGTMLADFYIAWAYSYDLSGNMRKADEIFRLGLECRAEPLEDLKEAHH 175
            :...|.....:.|....|||..:.||.|:|..|:.......|::::|||::..|||:::|::::.
plant    83 DFVDDPRALLRTMEAKSIGTKRSLFYQAYALHYEKMKRFEDAEKMYRLGVQNLAEPMDELQKSYL 147

  Fly   176 HFGYTVGQRMLYST---GEEANAVNQELNERRLALQSLHGRRQQISNSI---TVGSIRTGAAVKS 234
            .|...:.:.....|   .::.:..:.:::||:        :.:.:.|.:   .||......|...
plant   148 QFVTRMERHKKKKTQRQEQKLSGKHHKVDERQ--------QHEPVLNFVDKAIVGKPEAENACHH 204

  Fly   235 GL--PGV----------------VQVEPSTTTSRR------NVGRN--VEVFNDENSEGNIPISN 273
            ||  |.:                ::..|....||:      |.|.|  .|||.|||.|
plant   205 GLVDPTINMKEAMNTINNMFKEPIETAPLQRRSRQRSQNKENQGCNNSFEVFLDENLE------- 262

  Fly   274 SETEVKSSLRSIIDSACSQENIKEPVAWNKANAKRHKHGKIFGSNASPDLGFDIHVDEQAMPPIT 338
            .||......::......||.|.:                           .|:|.:|::......
plant   263 CETGTSGKAKTSTTQCGSQPNQE---------------------------SFEIFIDDENTDETA 300

  Fly   339 NYERRLEQPFRF--PTNFVAKNRPQEPWVTP----------------VTIEDEPNASGLPCYNKC 385
            :......:.|.|  |.:...::..:....||                .||.|||.|....|::.
plant   301 DENDEAGKAFVFLLPRDHSPESSEEADRNTPPRARFREDTVVRRFVGSTISDEPEAVENACHHG- 364

  Fly   386 LLYPRPNIEFSPEEYRAYSFLKHRNPQHPFIHRNDDWWGTGRVIRGIRCYP-NFARYSKPQDLDE 449
            |:.|..|::.:.|:                             |..:...| ||.|.::.::..:
plant   365 LVDPTVNLKEAMED-----------------------------INNMFGEPINFVRPNRSKNKGK 400

  Fly   450 LDKFWKPPLVPGLQVVFDKIYNEVEQK---EYQPEELLAAKWMEKRNVTVHGDFDMEETVC 507
            .....||....|..::.|....|.||:   :.||.:.|.:| .::|.:       .|.|||
plant   401 AVVETKPNPAAGFSILEDDDEEEAEQEHQGKSQPTQRLPSK-SDEREL-------FEPTVC 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BubR1	NP_477382.1	Mad3_BUB1_I	38..159	CDD:285506	31/112 (28%)
BubR1	NP_477382.1	STKc_Bub1_BubR1	1174..1458	CDD:270883
AT5G05510	NP_196170.1	Mad3_BUB1_I	9..131	CDD:214817	31/112 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1166
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1411806at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14030
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920