DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment BubR1 and AT2G20635

DIOPT Version :9

Sequence 1:	NP_477382.1	Gene:	BubR1 / 35522	FlyBaseID:	FBgn0263855	Length:	1460	Species:	Drosophila melanogaster
Sequence 2:	NP_179656.4	Gene:	AT2G20635 / 816591	AraportID:	AT2G20635	Length:	525	Species:	Arabidopsis thaliana

Alignment Length:	475	Identity:	117/475 - (24%)
Similarity:	211/475 - (44%)	Gaps:	101/475 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly  1022 RKAPVNENVGISKQPDEFFELNAATEMFATNIS-MIKNSTLLIPNAKVAEASELSIYYKTTPLTP 1085
            |:|......|:|::.:.|..|..|..:|...|| ..|.|:|    .||.:.::
plant   108 RRANSVYQTGLSRKAEPFDRLKEAHSLFLQRISKRTKASSL----EKVGDDAQ------------ 156

  Fly  1086 KQSHRSWSQSDLETPPRENFVHPTSNGDQTVLNETLADANKNPFNVELISSLLESI--------D 1142
                    .:||||    .||                    ||:....::.|:..|        .
plant   157 --------ATDLET----GFV--------------------NPWETSTVNGLIHKIKPQLVKYDG 189

  Fly  1143 FSMYIEKLPHCQLVGHVKRLHPNTHLEVHNEKFEVSKMIGKGAYGSVYVGKHLKSG--KKVALKQ 1205
            :.:..:..|....:..::....|..:|:...|:::....|:|.:..|:.. .:.|.  :.||||.
plant   190 YHVSNKVFPGKANLSSLQNYSRNKIIEIGGRKYQMKGCAGQGGFAQVFKA-FIDSNPDEVVALKV 253

  Fly  1206 ERPTNYWEFYICLEIHSRLTSEQMIPSYAHIDYALVGNNSSVYISEFSDYGSLIGVCNKVKSVTN 1270
            ::|...|||::..::..|:...|. .|:.......|.::.|:.:.::..:|:|..|.|.. .|..
plant   254 QKPPFPWEFHMYRQLDCRIPDSQR-SSFGLAQRVHVYSDYSILVCDYLSHGTLQDVINSY-VVVG 316

  Fly  1271 RNMDEYVVMHLSCQMLDIVDHLHAMGIIHADIKPDNFLLMKPICADPNEVS-------------- 1321
            ::|:|.:.|:.:.:||::::.||::||||.|.||||.|:..|    |..::
plant   317 KSMEEVLCMYYTIEMLNMLETLHSVGIIHGDFKPDNLLIRYP----PENLTETGFHEKTGSWSKK 377

  Fly  1322 -LQLIDFGVSIDMKLFPDNQTFNYVHHDDLFKCIEMRTGRPWTYQLDLYGLVSVMHVLLFGRYME 1385
             |.|:|:|..||:.|||....|........|:|:||:..:||.:|:|.|||..::|::|...|||
plant   378 GLCLVDWGRGIDLSLFPRTTEFTGDCRTSGFRCVEMKEDKPWKFQVDTYGLCVIVHMMLHNVYME 442

  Fly  1386 VVQRSP---STIWMPKTNVPRYFQRTMWENIFRTLLNIRDC----RTMPNLQQLRTQLKCALAEK 1443
            :.::..   ..|.||:|:..||::..:|:.:|..|||...|    .|:.||::          ..
plant   443 IEKKQSLDGGYINMPRTSFKRYWKVDLWKELFTKLLNRETCEDDTETLRNLRK----------SM 497

  Fly  1444 EKYVA---EAISKFNTILQK 1460
            |:|:.   :.:.|.|.:|.|
plant   498 EEYICSDPKLMKKLNELLAK 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BubR1	NP_477382.1	Mad3_BUB1_I	38..159	CDD:285506
BubR1	NP_477382.1	STKc_Bub1_BubR1	1174..1458	CDD:270883	87/310 (28%)
AT2G20635	NP_179656.4	Mad3_BUB1_I	11..117	CDD:415026	2/8 (25%)
AT2G20635	NP_179656.4	PKc_like	229..515	CDD:419665	86/302 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	113	1.000	Domainoid score	I2040
eggNOG	1	0.900	-	-		E1_KOG1166
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	218	1.000	Inparanoid score	I1216
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1411806at2759
OrthoFinder	1	1.000	-	-		FOG0004065
OrthoInspector	1	1.000	-	-		otm2686
orthoMCL	1	0.900	-	-		OOG6_103677
Panther	1	1.100	-	-	LDO	PTHR14030
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2819
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.870