DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and Slc17a6

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_445879.1	Gene:	Slc17a6 / 84487	RGDID:	620531	Length:	582	Species:	Rattus norvegicus

Alignment Length:	477	Identity:	138/477 - (28%)
Similarity:	241/477 - (50%)	Gaps:	36/477 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RHMQALLLFLAIVVNYTARLSVSVAIVAMTDAATTN------LDFPEYNWNGVQQSYILSSFYWG 71
            |::.|::..|...:::..|.::.||||.|.:.:|.:      .:..::||:......|..||:||
  Rat    70 RYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNWDPETVGMIHGSFFWG 134

  Fly    72 YIVTQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTPYC--VAWGGWQAFCTI--RIVEGLFQGLI 132
            ||:||.|.|::..|..|..|.....|.|:.|:.|.|..  |.:|     |.|  ||::||.:|:.
  Rat   135 YIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYG-----CVIFVRILQGLVEGVT 194

  Fly   133 FPCIHEHLAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGLIANGSMGWPGIFYVSAGTCGLWCL 197
            :|..|...:||:||.:|:||...::.|:..|:|:||..:|::...: ||..:|||......:|.:
  Rat   195 YPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYT-GWSSVFYVYGSFGMVWYM 258

  Fly   198 LWVLFGANNAPSSRLIGSREREHIERSMKRQDGF--HAQKIPIPWRAIWSSSPFYALLVVRSAQG 260
            .|:|....:......|...||.:||.|:......  ..:|...|||..::|.|.||::|....:.
  Rat   259 FWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRS 323

  Fly   261 WANSTMQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYLVFADVAMSRQWMSLTTLRKSI 325
            |....:.:..|:|...|...:|....:.||:|.|.|..:..:....||...|:|.:|.||:||.:
  Rat   324 WTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIM 388

  Fly   326 NTVSYWGPAAALIGIGFLDKSQTT-LAIALMTINAGLNAGSGIGSILTIIDMSPNHSGMLMAIVN 389
            |...:...|..|:.:|:   |.|. :||:.:.:..|.:..:..|..:..:|::|.::.:||.|.|
  Rat   389 NCGGFGMEATLLLVVGY---SHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISN 450

  Fly   390 GIGNIFPLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFFIGNLVYLIWGTTDQQAWDAEDYLQAK 454
            |:|.:..::.|::||. :|::.||.:||.||.:.|:|.:.|.:.|.::.:.::|.|        .
  Rat   451 GVGTLSGMVCPIIVGA-MTKNKSREEWQYVFLIAALVHYGGVIFYALFASGEKQPW--------A 506

  Fly   455 DPESESN-----AHQMEFKSRT 471
            |||..|.     .|:.|....|
  Rat   507 DPEETSEEKCGFIHEDELDEET 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	131/448 (29%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	127/431 (29%)
Slc17a6	NP_445879.1	2A0114euk	70..511	CDD:129972	134/458 (29%)
Slc17a6	NP_445879.1	MFS	75..498	CDD:119392	127/432 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	1.000	Domainoid score	I11657
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810