DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and slc17a7a

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_001092225.1	Gene:	slc17a7a / 795293	ZFINID:	ZDB-GENE-050105-5	Length:	582	Species:	Danio rerio

Alignment Length:	457	Identity:	141/457 - (30%)
Similarity:	241/457 - (52%)	Gaps:	26/457 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RHMQALLLFLAIVVNYTARLSVSVAIVAMTDAATTN------LDFPEYNWNGVQQSYILSSFYWG 71
            |::.|:|..|...:::..|.::.||||:|.:..|..      :...::.|:......|..||:||
Zfish    62 RYIIAILSGLGFCISFGIRCNLGVAIVSMVNDHTVYSGKKPVIVAAQFTWDPETVGMIHGSFFWG 126

  Fly    72 YIVTQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTPYC--VAWGGWQAFCTI--RIVEGLFQGLI 132
            |||||.|.||:.::|.|..|.....:||:.|:.|.|..  |.:|     |.|  |:.:||.:|:.
Zfish   127 YIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIPSAARVHYG-----CVIMVRVCQGLVEGVS 186

  Fly   133 FPCIHEHLAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGLIANGSMGWPGIFYVSAGTCGL-WC 196
            :|..|...|||:||.:|:||...|:.|:..|:|:||..:|::...: ||..:||| .|:.|: |.
Zfish   187 YPACHGIWAKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQYT-GWSSVFYV-YGSVGIFWY 249

  Fly   197 LLWVLFGANNAPSSRLIGSREREHIERSMKRQDGF--HAQKIPIPWRAIWSSSPFYALLVVRSAQ 259
            |.|:|....:..:...|...||::||.::....|.  ..||...|||..::|.|.||::|....:
Zfish   250 LFWILVSYESPAAHPTITPEERKYIEDAIGESAGLVNPLQKFKTPWRHFFTSMPVYAIIVANFCR 314

  Fly   260 GWANSTMQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYLVFADVAMSRQWMSLTTLRKS 324
            .|....:.:..|:|...|...:|....:.||||.|.|..:..:....||...:...|:.|.:||.
Zfish   315 SWTFYLLLISQPAYFEEVFGFEISKVGMVSALPHLVMTIIVPIGGQLADYLRTHNLMTTTNVRKL 379

  Fly   325 INTVSYWGPAAALIGIGFLDKSQTT-LAIALMTINAGLNAGSGIGSILTIIDMSPNHSGMLMAIV 388
            :|...:...|..|:.:||   |.|. :||:.:.:..|.:..:..|..:..:|::|.::.:||.|.
Zfish   380 MNCGGFGMEATLLLVVGF---SHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGIS 441

  Fly   389 NGIGNIFPLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFFIGNLVYLIWGTTDQQAW-DAEDYLQ 452
            ||:|.:..::.||:||. :|:..:|.:||.||.:.|:|.:.|.:.|.::.:.::|.| |||:..:
Zfish   442 NGVGTLSGMVCPLIVGA-MTKHKTREEWQYVFLIAALVHYGGVIFYGLFASGEKQPWADAENTSE 505

  Fly   453 AK 454
            .|
Zfish   506 EK 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	139/450 (31%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	133/432 (31%)
slc17a7a	NP_001092225.1	2A0114euk	62..501	CDD:129972	138/449 (31%)
slc17a7a	NP_001092225.1	MFS	67..490	CDD:119392	133/433 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582500
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.740