DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and slc17a5

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_001072823.1	Gene:	slc17a5 / 780284	XenbaseID:	XB-GENE-853687	Length:	496	Species:	Xenopus tropicalis

Alignment Length:	479	Identity:	148/479 - (30%)
Similarity:	246/479 - (51%)	Gaps:	44/479 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KGPV-IGIRHMQALLLFLAIVVNYTARLSVSVAIVAMTDAATT---------------------N 48
            |.|| ...|:..||:..|...:.|..|:::|||:|.|.::.:|                     |
Frog    32 KVPVCCSARYNLALMALLGFFMLYALRVNLSVALVDMVNSTSTPRENTTANICPDHTSAPAVLHN 96

  Fly    49 LDFPEYNWNGVQQSYILSSFYWGYIVTQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTPYCVAWG 113
            ....:|:|:...|.:||.||::|||:||.|.|::..:.|.|.:|....|.|||.:.|||....:|
Frog    97 STGQKYDWDANTQGWILGSFFYGYILTQIPGGYVAGKIGGKQLLGFGILGTAVFTLLTPLAADFG 161

  Fly   114 GWQAFC--TIRIVEGLFQGLIFPCIHEHLAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGLIAN 176
               |.|  .:|.:|||.:|:.||.:|...|:|:||.:|:||.:.:|:||..|:|:::..||||..
Frog   162 ---AGCLIAVRALEGLGEGVTFPAMHAMWARWAPPLERSRLLSLSYAGAQLGTVVSLPVSGLICY 223

  Fly   177 GSMGWPGIFYVSAGTCG-LWCLLWVLFGANNAPSSRLIGSREREHIERSMKRQDGFHAQKIPIPW 240
             .|.|..:||: .||.| ||.::|....::...|.|.|...|:|:|..:::.|..:...   :|.
Frog   224 -YMDWIYVFYI-FGTLGVLWFIMWCFLVSDTPQSHRSITDSEKEYILYTLQNQLSYRKS---VPC 283

  Fly   241 RAIWSSSPFYALLVVRSAQGWANSTMQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYLV 305
            .|:..|.|.:|::|...:..|...|:....|:||..:|..:.:.|...||||:|..|....:..|
Frog   284 CAMMKSLPLWAIIVAHFSYNWTFYTLLTLLPTYMKEILRFNAQENGFLSALPYLGCWVFMIMAGV 348

  Fly   306 FADVAMSRQWMSLTTLRKSINTVSYWGPAAALIGIGFLDKSQTTLAIALMTINAGLNAGSGIGSI 370
            .||....:..:|...:||..||:...|||..|:..|:.. ...:||:..:|::..|...|..|..
Frog   349 IADCLREKLNISTKVVRKIFNTLGMLGPAIFLLAAGYTG-CNYSLAVVFLTLSTTLGGFSVAGYG 412

  Fly   371 LTIIDMSPNHSGMLMAIVNGIGNIFPLLTPLLVGVIV----TESDSRSQWQIVFAMTAVVFFIGN 431
            :..:|::|:.:|:|:.|.|....|     |.:||.::    |..::..||||||.:.|.:.|.|.
Frog   413 INHLDIAPSFAGLLLGITNTFATI-----PGMVGPVIAKALTHDNTVEQWQIVFYIAAAINFFGA 472

  Fly   432 LVYLIWGTTDQQAWDAEDYLQAKD 455
            :.::|:.:.:.|.| |.|:...:|
Frog   473 IFFIIFASGNVQDW-AVDHNTEED 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	143/464 (31%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	137/446 (31%)
slc17a5	NP_001072823.1	MFS_SLC17A5	43..466	CDD:340939	135/436 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D619250at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010