DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7881 and slc17a7

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_001072608.1	Gene:	slc17a7 / 780064	XenbaseID:	XB-GENE-5742677	Length:	576	Species:	Xenopus tropicalis

Alignment Length:	504	Identity:	140/504 - (27%)
Similarity:	255/504 - (50%)	Gaps:	47/504 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRDNEKGPVI-----GI--RHMQALLLFLAIVVNYTARLSVSVAIVAMTDAATTN------LDFP 52
            :::.::.||:     |:  |::.|::..|...:::..|.::.||||:|.:..|..      ::..
Frog    43 IKEEKRQPVVDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNNTVYKGNKIVIEQA 107

  Fly    53 EYNWNGVQQSYILSSFYWGYIVTQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTP-------YCV 110
            ::.|:......|..||:|||||||.|.|::.::|.|..|.....:||:.|:.|.|       .||
Frog   108 QFTWDPETVGMIHGSFFWGYIVTQIPGGYICQKFAANRVFGFAIVATSTLNMLIPSAARVHFACV 172

  Fly   111 AWGGWQAFCTIRIVEGLFQGLIFPCIHEHLAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGLIA 175
                   .| :||::||.:|:.:|..|...:||:||.:|:||...|:.|:..|:|:||..:|::.
Frog   173 -------IC-VRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLV 229

  Fly   176 NGSMGWPGIFYVSAGTCGLWCLLWVLFGANNAPSSRLIGSREREHIERSMKRQDGF--HAQKIPI 238
            ..| ||..:|||......:|.:.|:|....:......|...|:::||.|:....|.  ...|...
Frog   230 QYS-GWSSVFYVYGSFGIMWYMFWILVSYESPAIHPTISEEEKKYIEESIGESTGLMNPMAKFKA 293

  Fly   239 PWRAIWSSSPFYALLVVRSAQGWANSTMQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVY 303
            |||..::|.|.||::|....:.|....:.:..|:|...|...:|....|.||||.|.|..:..:.
Frog   294 PWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGLLSALPHLVMTIIVPIG 358

  Fly   304 LVFADVAMSRQWMSLTTLRKSINTVSYWGPAAALIGIGFLDKSQTTLAIALMTINAGLNAGSGIG 368
            ...||...:::.||.|.:||.:|...:...|..|:.:|:  .....:||:.:.:..|.:..:..|
Frog   359 GQIADFLRTKRIMSTTNVRKMMNCGGFGMEATLLLVVGY--SHSRGVAISFLVLAVGFSGFAISG 421

  Fly   369 SILTIIDMSPNHSGMLMAIVNGIGNIFPLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFFIGNLV 433
            ..:..:|::|.::.:||.|.||:|.:..::.||:||. :|:..:|.:||.||.:.::|.:.|.|.
Frog   422 FNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGA-MTKHKTREEWQYVFLIASLVHYGGVLF 485

  Fly   434 YLIWGTTDQQAWDAEDYLQAKDPESESN-----AHQMEFKSRTDSEAKA 477
            |.|:.:.::|.|        .:||..|:     .|:.|....::.:::|
Frog   486 YGIFASGEKQPW--------AEPEETSDEKCGFIHEDELADESEEQSQA 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	131/453 (29%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	126/433 (29%)
slc17a7	NP_001072608.1	2A0114euk	62..503	CDD:129972	133/460 (29%)
		MFS	67..490	CDD:119392	127/434 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	517..547		1/10 (10%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910