DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7881 and Slc17a4

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_001258143.1	Gene:	Slc17a4 / 679784	RGDID:	1584758	Length:	495	Species:	Rattus norvegicus

Alignment Length:	473	Identity:	134/473 - (28%)
Similarity:	237/473 - (50%)	Gaps:	45/473 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IRHMQALLLFLAIVVNYTARLSVSVAIVAM--TDAA------------TTNLDF----------P 52
            :||..|.:|.|.....||.::::|:||.||  |.||            |.:.||          |
  Rat    35 LRHGLAFILHLCNFSVYTQQMNLSIAITAMVNTTAASSHANASIERPTTDSQDFWNETLQESKAP 99

  Fly    53 EYNWNGVQQSYILSSFYWGYIVTQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTPYCVAWGGWQA 117
            .|:|....|..:|||..:|..:...|.|::...||||.|:.:..|.::||:...| ..|..|...
  Rat   100 VYDWTPEIQGILLSSLNYGSFLAPIPTGYVAGVFGAKYVVGLGLLVSSVLTLFIP-LAAEAGVAL 163

  Fly   118 FCTIRIVEGLFQGLIFPCIHEHLAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGLIANGSMGWP 182
            ...:|:::|:.|.::....:...|||:||.:|::|...|.||:..|:.|.:.:.||:.. ::|||
  Rat   164 LIVLRVIQGMSQVMVLTGQYSMWAKWAPPLERSQLITIAASGSMLGTFLVLIAGGLLCQ-ALGWP 227

  Fly   183 GIFYVSAGTCGLWCLLWVLFGANNAPSSRLIGSREREHIERSMKRQDGFHAQKIPIPWRAIWSSS 247
            .|||:..|.....||||.....::..:...|.:.|:.:|..|:.::|......:||  :|:..|.
  Rat   228 YIFYIFGGIGCACCLLWFPLVYDDPQNHPFISTGEKRYIMCSLAQEDCSLGWSLPI--KAMVKSL 290

  Fly   248 PFYALLVVRSAQGWANSTMQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYL--VFADVA 310
            |.:|::|....:.|...|:...||:|:..||:.:::.:.:.|||||  |:|...:.|  :.||..
  Rat   291 PLWAIVVSYFCEYWLLFTIMAYTPTYISSVLQANLRDSGILSALPF--MFGCVCIILGGLLADFL 353

  Fly   311 MSRQWMSLTTLRKSINTVSYWGPAAALIGIGFLDKS-QTTLA-IALMTINAGLNAGSGIGSILTI 373
            :||..:.|.|:||....:.....:..|:.:.::..| .||:| :.|.::.|.|   ...|:::..
  Rat   354 LSRNILRLVTIRKLFTALGVLVSSGILVPLPWVSSSLSTTMAFLVLSSVFASL---CDSGALINF 415

  Fly   374 IDMSPNHSGMLMAIVNGIGNIFPLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFFIGNLVYLIWG 438
            :|::|.::|.|..::.....:...:.|.:.|..::: ||...|:.||.:.|.:..:|.|.|||:|
  Rat   416 LDIAPRYAGFLKGLLQVFSYLAGGIAPTVAGFFISQ-DSEFGWRNVFLLAAAIDVVGLLFYLIFG 479

  Fly   439 TTDQQAWDAEDYLQAKDP 456
            ..:.|.|       ||:|
  Rat   480 RAEVQDW-------AKEP 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	131/464 (28%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	124/446 (28%)
Slc17a4	NP_001258143.1	MFS_SLC17	40..479	CDD:340876	126/448 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342520
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840