DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and si:ch1073-513e17.1

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	XP_005159826.1	Gene:	si:ch1073-513e17.1 / 571066	ZFINID:	ZDB-GENE-030131-7188	Length:	508	Species:	Danio rerio

Alignment Length:	507	Identity:	153/507 - (30%)
Similarity:	254/507 - (50%)	Gaps:	60/507 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 RDNEKGPVI--------------GIRHMQALLLFLAIVVNYTARLSVSVAIVAM----TDAATTN 48
            :|::..|::              .:|...|:::|....|.|..|:::|||:|||    .|..::|
Zfish    16 QDSDTAPLLEKEVQEIKVPPKCCSVRCNLAVMMFFGFAVVYGLRVNLSVAMVAMVNGTNDQPSSN 80

  Fly    49 LD------------------------FPEYNWNGVQQSYILSSFYWGYIVTQFPAGFLVRRFGAK 89
            ..                        .|.|.||...|..:|.:|::||:.||.|.|:|..|||..
Zfish    81 SSISNECPAPSPAHNNNSQSSEQPEGIPRYPWNSETQGMLLGAFFFGYLFTQIPGGYLSGRFGGS 145

  Fly    90 AVLLVPTLATAVLSGLTPYCVAWGGWQAFCTIRIVEGLFQGLIFPCIHEHLAKWSPPEDRNRLGA 154
            ..|....|.||:|:.|||.....|....| .:|.:||..:|:.||.:....|:|:||.:|.||..
Zfish   146 LFLGGGVLGTALLTLLTPLSAQLGAKWLF-ALRALEGFGEGVTFPAMMAMWARWAPPLERARLMT 209

  Fly   155 FAYSGADCGSVLAMASSGLIANGSMGWPGIFYVSAGTCGLWCLLWVLFGANNAPSSRLIGSRERE 219
            |:.:|:..|:.:|:..:|.|.: |:|||.:||...|...||.:.|.:..::...:...|..:|::
Zfish   210 FSGAGSSFGAFVALPLTGFICH-SLGWPAVFYSCGGAGCLWAVFWFILVSDEPRTHPRITVQEKD 273

  Fly   220 HIERSMKRQDGFHAQKIPIPWRAIWS---SSPFYALLVVRSAQGWANSTMQLQTPSYMHGVLEMD 281
            :|..|:.:|...|...:|     :||   |.|.:|:::.:....|:..|:....|.||..||..|
Zfish   274 YIINSLGQQGTAHGWSVP-----VWSMLFSMPLWAIIIPQMCSNWSYYTLLTSLPIYMDTVLHFD 333

  Fly   282 IKSNALYSALPFLAMWGMSYVYLVFADVAMSRQWMSLTTLRKSINTVSYWGPAAALIGIGFLDKS 346
            ::.|:..||||:||.|..|....|.||..:.::.:|:|.:||....:..:.|||.|:.:||...|
Zfish   334 LRQNSFLSALPYLAGWLFSVGSGVLADNLLEKEILSVTAVRKIFTFIGLFLPAAFLLAVGFSGCS 398

  Fly   347 QTTLAIALMTINAGLNAGSGIGSILTIIDMSPNHSGMLMAIVNGIGNIFPLLTPLLVGVIVTESD 411
             ..||:..:|:::.....|..|..:..||::|.::|||:.|.|..|.|..:|.|::||.. |::.
Zfish   399 -GVLAVTFLTLSSAFGGFSAAGVFINQIDIAPRYAGMLLGITNTFGTIPGVLAPIVVGYF-TKNH 461

  Fly   412 SRSQWQIVFAMTAVVFFIGNLVYLIWGTTDQQAWDAEDYLQAKDPESESNAH 463
            |.|.|:.||.::|.|...|.:.|:|:||...|:|      ...|.||:::.|
Zfish   462 SVSGWRNVFWLSAGVSAFGAIFYVIFGTGKIQSW------ARTDEESDTDEH 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	147/467 (31%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	140/449 (31%)
si:ch1073-513e17.1	XP_005159826.1	2A0114euk	32..500	CDD:129972	147/482 (30%)
si:ch1073-513e17.1	XP_005159826.1	MFS	112..487	CDD:119392	126/383 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582542
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.740