DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and slc17a8

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_001076304.1	Gene:	slc17a8 / 563467	ZFINID:	ZDB-GENE-060503-416	Length:	590	Species:	Danio rerio

Alignment Length:	468	Identity:	138/468 - (29%)
Similarity:	241/468 - (51%)	Gaps:	43/468 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RHMQALLLFLAIVVNYTARLSVSVAIVAMTDAATTNLDF------PEYNWNGVQQSYILSSFYWG 71
            |::.|:|..|...:::..|.::.||||.|.:..|..::.      .::||:......|..||:||
Zfish    75 RYIIAMLSGLGFCISFGIRCNLGVAIVEMVNNNTVYINGTAVMQPAQFNWDPETVGLIHGSFFWG 139

  Fly    72 YIVTQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTPY-------CVAWGGWQAFCTIRIVEGLFQ 129
            |||||.|.||:..:..|..|.......|:||:...|.       ||.:        :||::||.:
Zfish   140 YIVTQIPGGFISNKLAANRVFGAAIFLTSVLNMFIPSAARVHYGCVMF--------VRILQGLVE 196

  Fly   130 GLIFPCIHEHLAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGLIANGSMGWPGIFYVSAGTCG- 193
            |:.:|..|...:||:||.:|:||...::.|:..|:|:||..:|::.. .:|||.:||: .|..|
Zfish   197 GVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQ-YVGWPSVFYI-YGVFGI 259

  Fly   194 LWCLLWVLFGANNAPSSRLIGSREREHIERSMKRQDGFH----AQKIPIPWRAIWSSSPFYALLV 254
            :|.:.|:|...|:......|...||.:||.|:  .:|.:    .:|...|||..::|.|.||::|
Zfish   260 IWYIFWILLAYNSPAVHPTISEEERNYIETSI--GEGANLMSSTEKFKTPWREFFTSMPVYAIIV 322

  Fly   255 VRSAQGWANSTMQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYLVFADVAMSRQWMSLT 319
            ....:.|....:.:..|:|...|....|....:.||:|.:.|..:..:....||...||:.:|.|
Zfish   323 ANFCRSWTFYLLLISQPAYFEEVFGFPISKVGILSAVPHMVMTIIVPIGGQLADFLRSRKILSTT 387

  Fly   320 TLRKSINTVSYWGPAAALIGIGFLDKSQT-TLAIALMTINAGLNAGSGIGSILTIIDMSPNHSGM 383
            |:||.:|...:...|..|:.:||   |.| .:||:.:.:..|.:..:..|..:..:|::|.::.:
Zfish   388 TVRKIMNCGGFGMEATLLLVVGF---SHTRAVAISFLILAVGFSGFAISGFNVNHLDIAPRYASI 449

  Fly   384 LMAIVNGIGNIFPLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFFIGNLVYLIWGTTDQQAWDAE 448
            ||.|.||:|.:..::.||:||.: |:..:|.:||.||.:.::|.:.|.:.|.|:.:.::|.|
Zfish   450 LMGISNGVGTLSGMVCPLIVGAL-TKHKTRLEWQHVFVIASMVHYTGVIFYAIFASGEKQDW--- 510

  Fly   449 DYLQAKDPESESN 461
                 .|||:.|:
Zfish   511 -----ADPENTSD 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	134/454 (30%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	129/437 (30%)
slc17a8	NP_001076304.1	2A0114euk	75..514	CDD:129972	135/462 (29%)
		MFS	81..503	CDD:119392	130/437 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	526..590
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582524
Domainoid	1	1.000	42	1.000	Domainoid score	I12425
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.740