DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7881 and CG30265

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_001286747.1	Gene:	CG30265 / 37622	FlyBaseID:	FBgn0050265	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	452	Identity:	255/452 - (56%)
Similarity:	336/452 - (74%)	Gaps:	0/452 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KGPVIGIRHMQALLLFLAIVVNYTARLSVSVAIVAMTDAATTNLDFPEYNWNGVQQSYILSSFYW 70
            |||::|:||:|.||||..|...|..||:|.||:||||:|.:||.|||||:|...|:|||||||:|
  Fly     7 KGPLLGMRHVQTLLLFFNITCLYIGRLNVGVAVVAMTNAESTNPDFPEYDWTLTQKSYILSSFFW 71

  Fly    71 GYIVTQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTPYCVAWGGWQAFCTIRIVEGLFQGLIFPC 135
            |||:|||..|:|.:|:|.|:|:|..:.|:.:.|.|||..:.:|.|||:|.||::.|..|||||||
  Fly    72 GYIITQFLGGYLCKRYGVKSVMLWGSFASGIFSALTPLFIGFGEWQAYCGIRVLMGFAQGLIFPC 136

  Fly   136 IHEHLAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGLIANGSMGWPGIFYVSAGTCGLWCLLWV 200
            ||:|||:||||.:||||||.:::|.:||:|.||..||:||..::|||||.|||||....||..|.
  Fly   137 IHQHLARWSPPAERNRLGALSHTGIECGNVCAMFFSGMIAKSAIGWPGISYVSAGLALAWCAFWF 201

  Fly   201 LFGANNAPSSRLIGSREREHIERSMKRQDGFHAQKIPIPWRAIWSSSPFYALLVVRSAQGWANST 265
            :|.|:||..||.|...|..:||.|:|..:.:|...||:||.|||:|:||:||:|.|..:.|..||
  Fly   202 VFAADNAEESRYITQEELHYIESSLKHNEDYHKTVIPVPWMAIWTSAPFFALMVARCCETWGLST 266

  Fly   266 MQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYLVFADVAMSRQWMSLTTLRKSINTVSY 330
            :|.|.|:||:|||:||:||||.:|||||||||.||||||:.|||.::...:|||.|||..|::::
  Fly   267 LQAQIPTYMNGVLDMDMKSNAFFSALPFLAMWIMSYVYLIIADVLLAGNRLSLTALRKIFNSLAF 331

  Fly   331 WGPAAALIGIGFLDKSQTTLAIALMTINAGLNAGSGIGSILTIIDMSPNHSGMLMAIVNGIGNIF 395
            |.|.|.||||||||:.|..||||||||:.|:|:|:.|||.|..||:||||:.:||.|||...|:.
  Fly   332 WIPCATLIGIGFLDQEQKNLAIALMTISVGVNSGATIGSSLNTIDLSPNHASILMGIVNTAANVV 396

  Fly   396 PLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFFIGNLVYLIWGTTDQQAWDAEDYLQAKDPE 457
            |::|||.||:||.|..:|.:|||||.:.||:|||||.|:|.:||...|.|||||||..|.|:
  Fly   397 PIVTPLAVGLIVHEDKNREEWQIVFIIAAVIFFIGNCVFLYYGTAVSQPWDAEDYLTEKVPD 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	245/436 (56%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	236/418 (56%)
CG30265	NP_001286747.1	2A0114euk	14..450	CDD:129972	245/435 (56%)
CG30265	NP_001286747.1	MFS	18..438	CDD:119392	236/419 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442680
Domainoid	1	1.000	42	1.000	Domainoid score	I12425
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D428976at33208
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	10	9.900