DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and MFS12

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_610332.3	Gene:	MFS12 / 35745	FlyBaseID:	FBgn0033234	Length:	477	Species:	Drosophila melanogaster

Alignment Length:	468	Identity:	180/468 - (38%)
Similarity:	282/468 - (60%)	Gaps:	16/468 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 IGIRHMQALLLFLAIVVNYTARLSVSVAIVAMTDAATTNLDFPEYNWNGVQQSYILSSFYWGYIV 74
            :|:||.||:|||:.:::||..|:::|.|||.||.:..   ..|.|.|:...:|.|||||:|||:|
  Fly    15 LGVRHWQAVLLFVGMMINYFQRVNISAAIVPMTQSTA---GAPFYTWDTSDKSLILSSFFWGYVV 76

  Fly    75 TQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTPYCVAWGGWQAFCTIRIVEGLFQGLIFPCIHEH 139
            :|.|||.|.:|||||.||.:.|....:|....| ..|..|||:.|.:|::.||.||.::||:|..
  Fly    77 SQVPAGLLAKRFGAKLVLGLATAIGGILCFFHP-IAAKSGWQSICVLRVLTGLVQGTVYPCVHTL 140

  Fly   140 LAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGLIANGSMGWPGIFYVSAGTCGLWCLLWVLFGA 204
            ||||.|..:|..|....||||..|:.:.:.:||.|...||||||:||:|.|....|.||:....|
  Fly   141 LAKWVPRTERGLLTTGVYSGAQFGTAVILVTSGFIFESSMGWPGLFYLSGGLSLAWALLFFWQAA 205

  Fly   205 NNAPSSRLIGSREREHIERSMKRQDGFHAQKIPIPWRAIWSSSPFYALLVVRSAQGWANSTMQLQ 269
            |...::..|...|.|:|| |:...:. .:|.:|:||.:|:.|..||.||.......|...|:..:
  Fly   206 NEPVTASRISKGEVEYIE-SLTGSNS-SSQSMPVPWMSIFRSPAFYGLLAAHCGFTWGFYTLLTE 268

  Fly   270 TPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYLVFADVAMSRQWMSLTTLRKSINTVSYWGPA 334
            .|:||..||::::||||..|:||:.||..:.:|....:|:.::|..:|:||.||..|::..|||.
  Fly   269 MPTYMSMVLQLNVKSNAFLSSLPYFAMGLLCFVVSPISDLLINRGTISITTARKLFNSIGQWGPM 333

  Fly   335 AALIGIGFLDKSQTTLAIALMTINAGLNAGSGIGSILTIIDMSPNHSGMLMAIVNGIGNIFPLLT 399
            |.|||:|::...:.|.||.|:|:..|:|||...|.::..||:|||.:|.:|.:.|||..:..::.
  Fly   334 ACLIGLGYMTADEKTWAILLLTLAVGINAGCSCGYLINHIDLSPNFAGPMMGVTNGIAGVTSIIA 398

  Fly   400 PLLVGVIVTESDSRSQWQIVFAMTAVVFFIGNLVYLIWGTTDQQAWDAEDYLQAKDPESESNAHQ 464
            ||:||.||::.:..|||::||.:|..::.:.|.:::|:|....|.|:        :|.|.|:.
  Fly   399 PLVVGAIVSDEEDPSQWRMVFFITGGIYLVCNTIFVIFGKATIQIWN--------EPPSTSST-- 453

  Fly   465 MEFKSRTDSEAKA 477
            |..:|..::::|:
  Fly   454 MTLRSHQENDSKS 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	173/436 (40%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	165/418 (39%)
MFS12	NP_610332.3	MFS	23..436	CDD:119392	165/418 (39%)
MFS12	NP_610332.3	2A0114euk	25..447	CDD:129972	168/435 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45442722
Domainoid	1	1.000	42	1.000	Domainoid score	I12425
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D428976at33208
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	10	9.900