DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and CG3036

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_001260058.1	Gene:	CG3036 / 33695	FlyBaseID:	FBgn0031645	Length:	493	Species:	Drosophila melanogaster

Alignment Length:	493	Identity:	130/493 - (26%)
Similarity:	220/493 - (44%)	Gaps:	70/493 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRDNEKGPV------IGIRHMQALLLFLAIVVNYTARLSVSVAIVAM------------------ 41
            |.:.|||.:      :..|.:..||..|..::||..|:::::|||.|
  Fly     1 MSNTEKGGLQRVRNFLSCRQVLNLLTMLGFMLNYALRVNLTIAIVDMVRPNVTSAVNATLVGNST 65

  Fly    42 ---TDAATTNLDFPE--YNWNGVQQSYILSSFYWGYIVTQFPAGFLVRRFGAKAVLLVPTLATAV 101
               :.|:...:|..|  :.|:..|.:::|..|:||||:|:.|.|.|....|.:.|.....|..::
  Fly    66 AANSTASPDGVDVYEERFPWDSYQTNFVLGCFFWGYILTELPGGRLAELIGGRRVFGHSMLWASL 130

  Fly   102 LSGLTPYCVAWGGWQAFCTIRIVEGLFQGLIFPCIHEHLAKWSPPEDRNR---------LGAFAY 157
            |:.:|| ..|...:.....:|:|.|...|..:|.||...|.|.||.:|::         ||| |.
  Fly   131 LTLITP-LAAHINYVVLIVVRVVLGFMLGASWPAIHPVAAVWIPPMERSKFMSNMMASSLGA-AI 193

  Fly   158 SGADCGSVLAMASSGLIANGSMGWPGIFYVSAGTCGLWCLLWVLFGANNAPSSRLIGSREREHIE 222
            :...||.::::|          ||..:||::.....||.|.|..|......:...|.:.||..||
  Fly   194 TMPICGYLISVA----------GWASVFYLTGAVGLLWSLAWFTFVYETPATHPRISAEERREIE 248

  Fly   223 RSMKRQDGFHAQKIP--IPWRAIWSSSPFYALLVVRSAQGWANSTMQLQTPSYMHGVLEMDIKSN 285
            .::....   ::|.|  :||..:..|...:|:::......:...|:..|.|::|..:|..|||.|
  Fly   249 EAIGTTT---SKKRPSHVPWGQLLCSPAVWAIIICHGLAVFGFFTVVNQLPTFMSKILHFDIKQN 310

  Fly   286 ALYSALPFLAMWGMSYVYLVFADVAMSRQWMSLTTLRKSINTVSYWGPAAALIGIGFLDK----S 346
            .|:|:||:|..:.|:......||....:..:|.|..||...|.:...|...:|...||..    |
  Fly   311 GLFSSLPYLGKYVMAVASSYLADYLRKKGTLSTTATRKLFTTFALVIPGLLMIVQVFLGYDATWS 375

  Fly   347 QTTLAIALM---TINAGLNAGSGIGSILTIIDMSPNHSGMLMAIVNGIGNIFPLLTPLLVGVIVT 408
            .|..::||.   .:.||. .|:|       :|::||..|.:..:.|.:.:....|:..:||.:..
  Fly   376 VTIFSLALFAHGAVTAGY-LGNG-------LDIAPNFGGTIFGLANTLSSFGGFLSTSMVGALTY 432

  Fly   409 ESDSRSQWQIVFAMTAVVFFIGNLVYLIWGTTDQQAWD 446
            :..|...|||||.:.|..:....:|:.|.|:.:.|.|:
  Fly   433 KDQSFHSWQIVFWILAATYISAAVVFAILGSGELQPWN 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	126/476 (26%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	121/459 (26%)
CG3036	NP_001260058.1	2A0114euk	19..477	CDD:129972	126/475 (27%)
CG3036	NP_001260058.1	MFS	83..461	CDD:119392	108/400 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	8	7.960