DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and MFS17

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_001015096.2	Gene:	MFS17 / 3354861	FlyBaseID:	FBgn0058263	Length:	505	Species:	Drosophila melanogaster

Alignment Length:	482	Identity:	138/482 - (28%)
Similarity:	231/482 - (47%)	Gaps:	41/482 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LLLFLA---IVVNYTARLSVSVAIVAM--TDAATTN---------LDFPEYNWNGVQQSYILSSF 68
            :|.||:   .:|::..|..::.|:|||  .|.:|.|         |.....:...:.:|.::|||
  Fly    38 VLYFLSWSGFLVSFMMRNDMNFALVAMIANDNSTQNQSLIKSQQILGTGTDDQKTIVKSVVISSF 102

  Fly    69 YWGYIVTQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTPYCVAWGGWQAFCTIRIVEGLFQGLIF 133
            ||.|:::|...|.....||.|.|.....||||:.|.:.| ..|...:.|...:|.::|...||.:
  Fly   103 YWCYVLSQVVGGVATELFGTKCVFGWSQLATALCSFMMP-SAAQLHYIAVIVLRSIQGFASGLTW 166

  Fly   134 PCIHEHLAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGLIANGSMGWPGIFYVSAGTCGL-WCL 197
            |.::..:..|.|..:|:|..: ::.|...|..|.....|.|.: ..|||.||| :.||.|| ||:
  Fly   167 PAMYAIVGYWIPLTERSRFMS-SFQGFSIGIGLTYPLCGFILS-EWGWPYIFY-TTGTLGLGWCI 228

  Fly   198 LWVLFGANNAPSSRLIGSREREHIERSMKRQDGFHAQKIPIPWRAIWSSSPFYALLVVRSAQGWA 262
            ||.|...|.......|...|..:||.::|::.. .:.|:.:||..|:.|.|.:|:.:....:.:.
  Fly   229 LWYLLAFNTPREHPRITKDELNYIELNVKKEVN-SSVKVKVPWLQIFKSIPAWAIAITTFGRIFV 292

  Fly   263 NSTMQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYLVFADVAMSRQWMSLTTLRKSINT 327
            :....:..|::|..||:.:.::|...|.:||:..:..|.::...||..:..:.:.||.:||....
  Fly   293 HYIFIVNGPTFMGNVLKFNFETNGFLSGVPFICSYISSVLFCYIADKIVFYKVLCLTNVRKVFTA 357

  Fly   328 VSYWGPAAALIGIGFLDKSQTTLA---IALMTINAGLNAGSGIGSILTIIDMSPN--HSGMLMAI 387
            :|...|...:..||::|.....|.   ||::.|.|     |..|::..|||::||  ||..::|.
  Fly   358 LSQIIPGVLIYCIGYIDNVYILLTVWFIAVIFITA-----SYAGAMANIIDLAPNYGHSAAVLAF 417

  Fly   388 VNGIGNIFPLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFFIGNLVYLIWGTTDQQAWDAEDYLQ 452
            ...|......::||..|.|||:.||..||:.||.::|::..:..|.|.::||.:.|.|:..  |.
  Fly   418 CQTIHMSASFISPLTAGFIVTQEDSIDQWRRVFEVSAIISILTYLFYQLFGTAEIQTWNKG--LP 480

  Fly   453 AKDPESESNAHQMEFKSRTDSEAKADI 479
            ..|...|         .:..|.||.|:
  Fly   481 VNDDSDE---------GKVLSTAKDDL 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	131/450 (29%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	127/438 (29%)
MFS17	NP_001015096.2	2A0114euk	34..477	CDD:129972	131/448 (29%)
MFS17	NP_001015096.2	MFS	41..467	CDD:119392	126/435 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	8	7.960