DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and MFS3

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_608572.1	Gene:	MFS3 / 33292	FlyBaseID:	FBgn0031307	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	504	Identity:	129/504 - (25%)
Similarity:	235/504 - (46%)	Gaps:	62/504 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KGPVIG----IRHMQALLLFLAIVVNYTARLSVSVAIVAMTD----------------------- 43
            ||.::|    .|::.|||..:.:.:.|..::::|||:|||.:
  Fly     8 KGSILGKLVPARYVLALLGSIGMAIVYGLKVNLSVAMVAMVNHTAIKAHGDGGGHGGHGSVILSN 72

  Fly    44 -----------------AATTNLDFPEYNWNGVQQSYILSSFYWGYIVTQFPAGFLVRRFGAKAV 91
                             ..|..::...::|:...|..:||.::|||:|:|.|...:...|.||.|
  Fly    73 ASQVSLVEECNPPGGASNVTAKVEDGPFDWSEPLQGTLLSCYFWGYLVSQIPLAHVAENFSAKWV 137

  Fly    92 LLVPTLATAVLSGLTPYC--VAWGGWQAFCTIRIVEGLFQGLIFPCIHEHLAKWSPPEDRNRLGA 154
            :|.......|.:.|||..  :.:||   ...:|::||:..|..||.:|..:|.|:||.:|..:..
  Fly   138 MLFSVAINVVCTLLTPVFTELHYGG---LILMRVLEGVGGGASFPAMHVMIASWAPPTERMVMST 199

  Fly   155 FAYSGADCGSVLAMASSGLIANGSMGWPGIFYVSAGTCGLWCLLWVLFGANNAPSSRLIGSRERE 219
            ..|.|...|:.|::..:| :.:...||..:|||......:|.||||:...:|....|.|...||:
  Fly   200 IIYVGTSAGTALSILLAG-VCSAQWGWESVFYVMGALSCIWMLLWVILVQDNPNKQRFISLEERQ 263

  Fly   220 HIERSMKRQDGFHAQKI----PIPWRAIWSSSPFYALLVVRSAQGWANSTMQLQTPSYMHGVLEM 280
            .|..|:..:     ||.    .:||..:::|.||:|:|:..:...:......::.|.||..||:.
  Fly   264 MITSSLGTE-----QKTEHHPAVPWGKVFTSVPFWAILIAHTCSNFGWYMFLIEIPFYMKQVLKF 323

  Fly   281 DIKSNALYSALPFLAMWGMSYVYLVFADVAMSRQWMSLTTLRKSINTVSYWGPAAALIGIGFLDK 345
            ::.|||..||||:..|...|.......|...::..::.|..||:..::....|...|:.:.::.
  Fly   324 NVASNAALSALPYFPMIIFSICLGKLLDSLQAKGKITTTVARKTATSICTLIPGVCLLVLCYIG- 387

  Fly   346 SQTTLAIALMTINAGLNAGSGIGSILTIIDMSPNHSGMLMAIVNGIGNIFPLLTPLLVGVIVTES 410
            .:...|:::|::..........|.:...||::||.:|.|:|:.|....:..::.||.||.:...:
  Fly   388 CRHYEAVSVMSVGIVAMGSMFSGFLSNHIDIAPNFAGTLVALTNTAATLPGIVVPLFVGFVTKGN 452

  Fly   411 DSRSQWQIVFAMTAVVFFIGNLVYLIWGTTDQQAWDAEDYLQAKDPESE 459
            .:...|:|:|.:|.|:|.:..||::..|:..:|.|:...  ..||||::
  Fly   453 QNIGAWRIIFGVTIVLFALEFLVFVFLGSGSEQPWNKAG--TPKDPEAK 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	122/482 (25%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	117/464 (25%)
MFS3	NP_608572.1	2A0114euk	19..489	CDD:129972	122/479 (25%)
MFS3	NP_608572.1	MFS	100..479	CDD:119392	107/388 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D46132at33392
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	9	8.970