DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7881 and Slc17a8

DIOPT Version :9

Sequence 1:NP_001286144.1 Gene:CG7881 / 35521 FlyBaseID:FBgn0033048 Length:482 Species:Drosophila melanogaster
Sequence 2:NP_714947.1 Gene:Slc17a8 / 266767 RGDID:628870 Length:588 Species:Rattus norvegicus


Alignment Length:465 Identity:139/465 - (29%)
Similarity:239/465 - (51%) Gaps:40/465 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 RHMQALLLFLAIVVNYTARLSVSVAIVAMTDAATTNLD-FPE-----YNWNGVQQSYILSSFYWG 71
            |::.|::..|...:::..|.::.||||.|.:.:|..:| .||     :||:......|..||:||
  Rat    75 RYIIAVMSGLGFCISFGIRCNLGVAIVEMVNNSTVYVDGKPEIQTAQFNWDPETVGLIHGSFFWG 139

  Fly    72 YIVTQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTPY-------CVAWGGWQAFCTIRIVEGLFQ 129
            |||||.|.||:..:|.|..|.......|:.|:...|.       ||       .| :||::||.:
  Rat   140 YIVTQIPGGFISNKFAANRVFGAAIFLTSTLNMFIPSAARVHYGCV-------MC-VRILQGLVE 196

  Fly   130 GLIFPCIHEHLAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGLIANGSMGWPGIFYVSAGTCG- 193
            |:.:|..|...:||:||.:|:||...::.|:..|:|:||..:|::.. .:||..:||: .|..| 
  Rat   197 GVTYPACHGMWSKWAPPLERSRLATTSFCGSYAGAVVAMPLAGVLVQ-YIGWASVFYI-YGMFGI 259

  Fly   194 LWCLLWVLFGANNAPSSR-LIGSREREHIERSMKRQDGFHA-QKIPIPWRAIWSSSPFYALLVVR 256
            :|.:.|:| .|...|:.. .|.:.||.:||.|:.......: .|...|||..::|.|.||::|..
  Rat   260 IWYMFWLL-QAYECPAVHPTISNEERTYIETSIGEGANLASLSKFNTPWRRFFTSLPVYAIIVAN 323

  Fly   257 SAQGWANSTMQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYLVFADVAMSRQWMSLTTL 321
            ..:.|....:.:..|:|...|....|....|.||:|.:.|..:..:....||...||:.::.|.:
  Rat   324 FCRSWTFYLLLISQPAYFEEVFGFAISKVGLLSAVPHMVMTIVVPIGGQLADYLRSRKILTTTAV 388

  Fly   322 RKSINTVSYWGPAAALIGIGFLDKSQTT-LAIALMTINAGLNAGSGIGSILTIIDMSPNHSGMLM 385
            ||.:|...:...|..|:.:||   |.|. :||:.:.:..|.:..:..|..:..:|::|.::.:||
  Rat   389 RKIMNCGGFGMEATLLLVVGF---SHTKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILM 450

  Fly   386 AIVNGIGNIFPLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFFIGNLVYLIWGTTDQQAWDAEDY 450
            .|.||:|.:..::.||:||. :|:..:|.:||.||.:.|:|.:.|.:.|.::.:.::|.|     
  Rat   451 GISNGVGTLSGMVCPLIVGA-MTKHKTREEWQNVFLIAALVHYSGVIFYGVFASGEKQDW----- 509

  Fly   451 LQAKDPESES 460
               .|||:.|
  Rat   510 ---ADPENLS 516

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7881NP_001286144.1 2A0114euk 12..449 CDD:129972 135/452 (30%)
MFS 18..437 CDD:119392 131/435 (30%)
Slc17a8NP_714947.1 MFS_SLC17A6_7_8_VGluT 79..502 CDD:340940 132/437 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 539..588
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166342502
Domainoid 1 1.000 47 1.000 Domainoid score I11657
eggNOG 1 0.900 - - E1_KOG2532
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000034
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
65.740

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