DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and SPAC1002.16c

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_593504.1	Gene:	SPAC1002.16c / 2543262	PomBaseID:	SPAC1002.16c	Length:	499	Species:	Schizosaccharomyces pombe

Alignment Length:	459	Identity:	98/459 - (21%)
Similarity:	172/459 - (37%)	Gaps:	110/459 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 RDNEKGPV-IGIRHM-----QALLLFLAIVVNYTARLSVSVAIVAMTDAATTNL-DFPE-YNWNG 58
            |.|...|: |...|:     .:||..|.:|:..|..:...||.:..::.....: ..|| ....|
pombe    29 RSNTASPISIENTHLTKSERDSLLFRLDLVLAPTIMILYLVAFLDRSNIGNAKVAGLPEDLKLKG 93

  Fly    59 VQQSYILSSFYWGYIVTQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTPYCVAWGGWQAFCTIRI 123
            .|.:.|.|.||..:|:.:.|...|:::...|.:|....::.::.:..|.:|..:||..|   .|:
pombe    94 DQFNIIASVFYVTFILFEMPTTLLMKKVQPKRMLAFIVISYSLTTIFTGFCHNFGGLLA---ARL 155

  Fly   124 VEGLFQGLIFPCIHEHLAK-WSPPEDRNRLGAFAYSGADCGSVLAMASSGLIA---------NGS 178
            |.|..:..:|||:..:|.. :|..|...|:   ||..|  .|.|:.|..||.|         .|.
pombe   156 VLGFCEAGLFPCLALYLTMIYSRVELAPRI---AYLFA--SSALSGAFGGLFAYAVLHMDGVGGF 215

  Fly   179 MGWPGIFYVSAGTCGLWCLLWVLFGANNAPSSRLIGSREREHIERSMKRQDGFHAQKIPIPWRAI 243
            .||..:|.:. |..|..|.:.|.|...|..:.....|:..:.:.|..:.:.....:.....|:.:
pombe   216 AGWRWLFIIE-GLIGFVCGVAVYFIIPNDITKAWFLSKTHQEMMRKRQLERAADLEAAHFDWKGV 279

  Fly   244 WSSSPFYALLVVRSAQGWANSTMQLQTPSYMHGVLEMDIKSNALYSALPFL--AMWGMSYVYLVF 306
            .|:...:.:                    |::.:.|.. :...||....||  .:.||.|
pombe   280 KSAFTDFKV--------------------YLYALSEFG-QDTCLYGFSTFLPAIISGMGY----- 318

  Fly   307 ADVAMSRQWMSLTTLRKSINTVSYWGPAAALIGIGFL-DKSQTTLAIALMTINAGLNAGSGIGSI 370
              .::|.|:|::..         |...||..|...|| |:.
pombe   319 --TSLSVQYMTIPV---------YILGAATYIAASFLSDRF------------------------ 348

  Fly   371 LTIIDMSPNHSGMLMAIVNGIGNIFPLLTPLLVGVIVTESDSRSQWQIVFA--MTAVVFFIGNLV 433
                    :|.|:::.    ||||||     :||.|:..:...::..:.||  :.:|..:.|..:
pombe   349 --------HHRGIILI----IGNIFP-----IVGYILLLACQNNKSVLYFACYLCSVGVYTGAGL 396

  Fly   434 YLIW 437
            .:.|
pombe   397 NVTW 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	94/448 (21%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	92/435 (21%)
SPAC1002.16c	NP_593504.1	MFS	63..455	CDD:119392	88/425 (21%)
SPAC1002.16c	NP_593504.1	2A0114	65..435	CDD:273326	88/423 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050