DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and SPAC11D3.18c

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_001342807.1	Gene:	SPAC11D3.18c / 2543005	PomBaseID:	SPAC11D3.18c	Length:	498	Species:	Schizosaccharomyces pombe

Alignment Length:	484	Identity:	101/484 - (20%)
Similarity:	184/484 - (38%)	Gaps:	140/484 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PVIGIRHMQALLLFLAIVVNYTARLSV-SVAIVAMTDAATTNLDFPEYNWNGVQQSYILSSFYWG 71
            |:||..::.|.|          .|.:: :.|:..||:|.:.         .|.:.:..:|.||..
pombe    63 PIIGFLYLMAFL----------DRSNIGNAAVAGMTEALSL---------YGERLNVAVSIFYVL 108

  Fly    72 YIVTQFPAGFLVRRFGAKAVLLVPTLA---TAVLSGLTPYCVAWGGWQAFCTIRIVEGLFQGLIF 133
            ||:.:.|:..||:|..|..:|...:.|   |.:.||   :..::||   ....|::.||.:|.:|
pombe   109 YILVETPSVVLVKRIKASRMLAFISFAWSMTVLFSG---FMSSYGG---LIATRLILGLLEGCLF 167

  Fly   134 PCIHEHL-AKWSPPEDRNRLG-AFAYSG--ADCGSVLAMASSGLIANGSMGWPGIFYVSAGTCGL 194
            |.::.:| ..::..|...||. .||.:|  ...|.:.|.|...:.|....||..|:.|.    ||
pombe   168 PALNLYLTTHYTRKEQCQRLSYLFASAGLAGAFGGLFAYALEQVHAGNKEGWQWIYIVE----GL 228

  Fly   195 WCLLWV---LFGANNAPSSRLIGSRE-----------------REHIERSMKRQDGFHAQKIPIP 239
            ...:.|   ||...:...:....:||                 .:|.|.|..|: .|...|:.:.
pombe   229 VSFIGVPLCLFALPDKMENAWFLTREEREVAIIRRDINARYHGEQHFEWSEVRK-AFKDPKVYVS 292

  Fly   240 WRAIWSSSPFYALLVVRSAQGWANSTMQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYL 304
                 ::|.|.|.:|:.....:        .|..:.|:..:.:::|  |..:|......:|::::
pombe   293 -----ATSQFCADMVLYGFSSF--------LPVIIKGLGFVGLQTN--YMTIPVYIAGVISFLFV 342

  Fly   305 VFADVAMSRQWMSLTTLRKSINTVSYWGPAAALIGIGFL---------DKSQTTLAIAL-MTINA 359
            .         |:|..|..:::..:|    |:.::.:|::         .|...|..||: ..|..
pombe   343 A---------WLSDRTQLRAVYLIS----ASTVVAVGYIIMLASDSNAAKYTATYIIAIGCYIGP 394

  Fly   360 GLNAG-------------SGIGSILTIIDMSPNHSGMLMAIVNG----IGNIFPLLTPLLVGVIV 407
            |||.|             :.||...|:.:.|...:|.:....|.    :||.|.|      |.::
pombe   395 GLNLGWLNNNVAGHYKRATAIGIQQTLANSSGIVAGQIYRSKNAPKYILGNAFTL------GCVI 453

  Fly   408 TESDSRSQWQIVFAMTAVVFFIGNLVYLI 436
                                 :|.|.|::
pombe   454 ---------------------VGGLAYVV 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	98/480 (20%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	97/474 (20%)
SPAC11D3.18c	NP_001342807.1	UhpC	68..461	CDD:332119	98/477 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050