DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and vht1

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_594801.1	Gene:	vht1 / 2542518	PomBaseID:	SPAC1B3.16c	Length:	568	Species:	Schizosaccharomyces pombe

Alignment Length:	455	Identity:	91/455 - (20%)
Similarity:	163/455 - (35%)	Gaps:	137/455 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LLLFLAIVVNYTARLSVSVAIVAMTDAATTNLDFPEYNWNGVQQSYI---LSSFYWGYIVTQFPA 79
            :|.||:..:.:|..||.:     |..|...:|   ....:|....|:   |:.||.|||:.:.|:
pombe    91 ILYFLSCCLRFTVSLSFT-----MNTAQGHSL---IQTLSGYSAHYLALGLALFYVGYIIFEVPS 147

  Fly    80 ----GFLVRRFGAKAVLLVPTLATAVLSGLTPYCVA-----WGGWQAFCTIRIVEGLFQGLIFPC 135
                .|:..|.....:.|.        .|:...|.|     .|..|::..:|...|:.:..::|.
pombe   148 NLMMAFIEPRIWVSRIQLT--------IGVVGACHAVLGTKHGNAQSYVALRFFLGVAESGLWPG 204

  Fly   136 IHEHLAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGLIANGSMGWPGIFYVSAGTCGLWCLLW- 199
            :..::::|...:...:...:.|:.|.    :|.|:..|::.|       |....|..||:...|
pombe   205 LAYYMSRWYRGKHLGKRIGWYYTAAQ----IAAAAVSLVSAG-------FQKMDGARGLYGYQWM 258

  Fly   200 -VLFGANNAPSSRLIGSREREHIERSMKRQDGFHAQKIPIPWRAIWSSSPFYALLVVRSAQGWAN 263
             :::|....                         ||.:.|||   |       |..|.|.:...:
pombe   259 FLIWGVVAI-------------------------AQALSIPW---W-------LPAVASKEHRKS 288

  Fly   264 STMQLQTPSYMH-------GVLEMDIKSNALYSALPFLAMWGMSYVYLVFADVAMSRQWMSLTTL 321
            .:..:..|.:|.       |.|....||  |:|.            |:...:|....||   :.|
pombe   289 LSSFIPLPKWMKTLSPQRIGFLTPADKS--LHSR------------YIAEMNVGKRWQW---SDL 336

  Fly   322 RKSINTVSYWGPAAALIGIGFLDKSQTTLAIALMTINAGLNAGSGIGSILTII--DMSPNHSGML 384
            .||...:..|.......||                    :..|:||.:..|:|  :::|:.||:.
pombe   337 LKSCLDLRVWPFILMYFGI--------------------VGVGNGIFNYCTLIIEEINPSFSGID 381

  Fly   385 MAIVNGIGNIFPLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFFIGNLVYLIWGTT----DQQAW 445
            ::::|.     |:.....:| |||......::...|:     ||.|:.:.:|.|..    ..:||
pombe   382 ISLLNA-----PIWLADALG-IVTVMPLYDRFHKKFS-----FFTGSCLIIIAGLAVANYAPRAW 435

Fly 446 445
pombe 436 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	91/455 (20%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	87/441 (20%)
vht1	NP_594801.1	HpaX	80..503	CDD:131385	91/455 (20%)
vht1	NP_594801.1	MFS	94..493	CDD:119392	90/452 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000