DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and SPBPB10D8.01

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_595045.1	Gene:	SPBPB10D8.01 / 2541399	PomBaseID:	SPBPB10D8.01	Length:	552	Species:	Schizosaccharomyces pombe

Alignment Length:	460	Identity:	91/460 - (19%)
Similarity:	163/460 - (35%)	Gaps:	118/460 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RLSVSVAIVAM-------TDAATTNLD-----FPEYNWNGVQQSYILSSFYWGYIVTQFPAGFLV 83
            :|..:|.::.|       .|.||.:..     |.:.:.|..|.:.|.:.||.|:::.|.|...|:
pombe    84 KLYFTVLVMLMILDMMLYIDKATLSYSSILGLFEDTHINSNQYNDINTLFYVGFVIGQIPGHMLL 148

  Fly    84 RRFGAKAVLLVPTLATAVLSGLTPYCVAWGGWQAFCTIRIVEGLFQGLIFPCIHEHLAKWSPPED 148
            :||.....:...|....::..|  :|.|: .:.....:|...||.:..:.|.:...:..:.|..:
pombe   149 QRFPVSKFVAASTALWTIIIFL--HCAAY-NFSGLMALRFFLGLVESSLLPTMEATIGMFFPHSE 210

  Fly   149 RNRLGAFAY-SGADCGSVLAMASSGLIANGSMGWPGIFYVSAGTCGLWCLLWVLFGA-------- 204
            :..|..|.| |...|.     ..:|.||.      |:.| :..|...|.|..::.|.
pombe   211 QALLQPFFYISCYGCN-----IPAGFIAY------GVQY-AKNTISPWKLFMIIVGGITFFLTIG 263

  Fly   205 ------NNAPSSRLIGSRER----EHIERS---------MKRQDGFHAQKIPIPWRAIWSSSPFY 250
                  :|..::|.:..:||    :.:.||         .|:.....|.|.|:.|  :::...|.
pombe   264 LFFYYPDNTSTARFLTKKERLYTVDRVRRSNHSGIESKTFKKYQVIEALKDPVTW--LFTFHVFC 326

  Fly   251 ALLVVRSAQGWANSTMQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYLVFADVAMSRQW 315
            ..|        :|:.      :|...:|...:..:.|.|.|..:|..|.:.|..:.|...||
pombe   327 NQL--------SNNL------AYQQNLLFTSLNVSDLNSTLVGVASAGYNCVSAIIATYMMS--- 374

  Fly   316 MSLTTLRKSINTVSYWGPAAALIGIGFLDKSQTTLAIALMTINAGLNAGSGIGSILTIIDMSPNH 380
                                       :.|:|:....|:..|       ..|...:..:.||.:|
pombe   375 ---------------------------VIKNQSAFHGAIWYI-------PSIAGGIACVAMSWDH 405

  Fly   381 S-GMLMAIVNGIGNIFPLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFFIGNLVYLIWGTTDQQA 444
            . |.|.||:  |.:.|.:  |.::.:..|.:......:.:  ...|:|.||   |.|......|.
pombe   406 KIGELAAII--IASNFGI--PFIISLGWTTASCAGYTKKL--TRGVMFMIG---YAIANIIGPQM 461

  Fly   445 WDAED 449
            |.:.|
pombe   462 WQSRD 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	90/458 (20%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	87/446 (20%)
SPBPB10D8.01	NP_595045.1	MFS	90..492	CDD:119392	89/454 (20%)
SPBPB10D8.01	NP_595045.1	2A0114	101..497	CDD:273326	88/443 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050