DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and Slc17a9

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_898984.3	Gene:	Slc17a9 / 228993	MGIID:	1919107	Length:	447	Species:	Mus musculus

Alignment Length:	465	Identity:	109/465 - (23%)
Similarity:	184/465 - (39%)	Gaps:	116/465 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LLFLAIVVNYTARLSVSVAIVAMTDAATTNLDFPEYNWNGVQQSYILSSFYWGYIVTQFPAGFLV 83
            :|.|...:.|.||:::.|..|||:.         ::.||..:...:||||:|||.:||...|.|.
Mouse    40 ILLLGTCLLYCARVTMPVCTVAMSQ---------DFGWNKKEAGIVLSSFFWGYCLTQVVGGHLG 95

  Fly    84 RRFGAKAVLLVPTLATAVLSGLTPYCVAWG-GWQAFCTI-RIVEGLFQGLIFPCIHEHLAKWSPP 146
            .|.|.:.|:|:...|...::..||.....| |..||.|. ||:.||.||:.||.:...|::....
Mouse    96 DRIGGEKVILLSASAWGFITVTTPLLAHLGSGHLAFLTFSRILTGLLQGVYFPALTSLLSQKVQE 160

  Fly   147 EDRNRLGAFAYSGADCGS---VLAMASSGLIANGSMGWPGIFYVSAGTCGLWCLLWVLFGANNAP 208
            .:|    ||.||....||   .|.....|.:.....||..:||.|.|...||......:..|
Mouse   161 SER----AFTYSTVGAGSQVGTLVTGGVGSVLLDQCGWQSVFYFSGGLTLLWAYYVYRYLLN--- 218

  Fly   209 SSRLIGSREREHIERSMKRQDGFHAQKIP------IPWR------AIW--------SSSPFYALL 253
                         |:.:....||.||.:|      :|||      ::|        |:..|:.||
Mouse   219 -------------EKDLVLALGFLAQGLPVTKPSKVPWRQLFRKASVWAAICSQLCSACSFFILL 270

  Fly   254 ---------VVRSAQGWANSTMQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYLVFADV 309
                     ...:::||                         :::.:|    |.::....:|:..
Mouse   271 SWLPTFFKETFPNSKGW-------------------------VFNVVP----WMLAIPASLFSGF 306

  Fly   310 AMSR---QWMSLTTLRKSINTVSYWGPAAALIGIGF-----LDKSQTT---LAIALMTINAGLNA 363
            ...|   |...:.|:||.:.          ::|:|.     |....||   .|:...:.:.|...
Mouse   307 ISDRLISQGYRVITVRKFMQ----------VMGLGLSSIFALCLGHTTSFLKAMIFASASIGFQT 361

  Fly   364 GSGIGSILTIIDMSPNHSGMLMAIVNGIGNIFPLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFF 428
            .:..|..:.|.|::|:.:|.|..:.|..|.:..::...|.|.::   ::...|..||.:.|::..
Mouse   362 FNHSGISVNIQDLAPSCAGFLFGVANTAGALAGVVGVCLSGYLI---ETTGSWTCVFHLVAIISN 423

  Fly   429 IGNLVYLIWG 438
            :|...:|::|
Mouse   424 LGLGTFLVFG 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	109/465 (23%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	108/462 (23%)
Slc17a9	NP_898984.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		MFS	40..432	CDD:119392	108/462 (23%)
		2A0114	43..424	CDD:273326	105/451 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810