DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and Slc17a2

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	XP_006516709.1	Gene:	Slc17a2 / 218103	MGIID:	2443098	Length:	480	Species:	Mus musculus

Alignment Length:	474	Identity:	129/474 - (27%)
Similarity:	224/474 - (47%)	Gaps:	52/474 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IRHMQALLLFLAIVVNYTARLSVSVAIVAMT------DAATTNLDFP------------------ 52
            :|:..||::..:.....|.|:|:|:||:||.      |.|..:.:.|
Mouse    16 LRYALALIMHFSNFTMITQRVSLSIAIIAMVNSTQHQDPANASTEGPVMDLLSNQSRGIKDFSTR 80

  Fly    53 --EYNWNGVQQSYILSSFYWGYIVTQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTPYCVAWGGW 115
              .|.|:...|..|.||..:|.|:|..|:|:|...||||.:|....|.:::|:..||....:|..
Mouse    81 AAVYQWSTETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLISSLLTLFTPLAADFGVI 145

  Fly   116 QAFCTIRIVEGLFQGLIFPCIHEHLAKWSPPEDRNRLGAFAYSGADCGSV----------LAMAS 170
            ... .||.|:|:.||:.:.......|||:||.:|::|.:.|.||.|.|||          :.:..
Mouse   146 LVI-VIRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTSIAGSGEDVGSVWVLHHPLCGRINLTG 209

  Fly   171 SGLIANGSMGWPGIFYVSAGTCG-LWCLLWVLFGANNAPSSRLIGSREREHIERSMKRQDGFHAQ 234
            :||          .||:.....| :.|:||.....::......|..||:|||..|:.:|.....:
Mouse   210 TGL----------AFYLLHLCIGCVCCVLWFTVIYDDPMHHPCISVREKEHITSSVAQQSSSPRR 264

  Fly   235 KIPIPWRAIWSSSPFYALLVVRSAQGWANSTMQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGM 299
            .:||  :|:....|.:|:.:...:..|..:.:....|:|:..||.::|:.:.:.|:|||:|....
Mouse   265 SVPI--KAMVRCLPLWAIFMGFFSHFWLCTIIITYLPTYISTVLHVNIRDSGVLSSLPFIAASSC 327

  Fly   300 SYVYLVFADVAMSRQWMSLTTLRKSINTVSYWGPAAALIGIGFLDKSQTTLAIALMTINAGLNAG 364
            :.:....||..:||..:||.|:||..:::....|:...:.:.|:..|.....:.|:.|....|..
Mouse   328 TILGGQMADFLLSRNLLSLITVRKLFSSLGLLLPSLCAVALPFVTSSYIATIVLLILIPGTSNLC 392

  Fly   365 SGIGSILTIIDMSPNHSGMLMAIVNGIGNIFPLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFFI 429
            .. |.|:..:|::|.::..||.|..|.|....:::....|.:::: ||.|.|:.||.::|.|...
Mouse   393 DS-GFIINTLDVAPRYASFLMGISRGFGLTAGIISSTTTGFLISQ-DSESGWRNVFFLSAAVNMF 455

  Fly   430 GNLVYLIWGTTDQQAWDAE 448
            |.:.|||:|..:.|:|..|
Mouse   456 GLIFYLIFGQAEIQSWAKE 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	129/474 (27%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	122/455 (27%)
Slc17a2	XP_006516709.1	MFS_SLC17	21..464	CDD:340876	124/457 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838743
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.740