DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and Y15E3A.4

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_510539.1	Gene:	Y15E3A.4 / 181623	WormBaseID:	WBGene00012443	Length:	469	Species:	Caenorhabditis elegans

Alignment Length:	500	Identity:	110/500 - (22%)
Similarity:	213/500 - (42%)	Gaps:	62/500 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EKG----PVIGIRHMQALL----LFLA------IVVNYTARLSVSVAIVAMTDAATTNLDFPEYN 55
            |||    |.:..|....:|    |.:|      .|:|:|   .:.:|....:.|.|:|::.....
Worm     3 EKGSTLVPFLADRQRYIILAIGTLCIAAIASNMTVINFT---MICMAKPVNSSALTSNVEADNLA 64

  Fly    56 WNGVQQSYILSSFYWGYIVTQFPAGFLVRRFGAKAVL----LVPTLATAVLSGLTPYCVAWGGWQ 116
            ::..|:|.|:.:...|.:...:|..:...:|||::|.    :|.||:|||:.     ..|...:.
Worm    65 YSNKQKSIIMWAAAVGTLAAAWPFHWFYTQFGARSVFFAAGVVSTLSTAVMP-----LAAEVHFN 124

  Fly   117 AFCTIRIVEGLFQGLIFPCIHEHLAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGLIANGSMGW 181
            .....|..:|:..|..|..|...:..|:..:......:...|.:....:..|..:|.:...:.||
Worm   125 FLVVARFFQGVSFGADFAAIGLIVVNWASLKQHGLFISLLSSFSQISVMFTMPVAGELCESTWGW 189

  Fly   182 PGIFYVSAGTCGLWCLLWVLFGANNAPSSRLIGSREREHIERSMKRQDGFHAQKIPIP------- 239
            ..::||.|...|:....|:.|..:|......:...|.|.|.|.  :.|....:|.||.
Worm   190 QSVYYVHAVLSGVLFTAWLYFYRDNPTKHPQMTEIELEKIHRG--KGDVKEHEKAPIAKILTNSV 252

  Fly   240 WRAIWSSSPFYALLVVRSAQGWANSTMQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYL 304
            ..|:|.|: |..|::        :..:.:..|:::..||...:.....:.|:|    ..:...:.
Worm   253 MLAVWLSA-FGELMM--------SQFIVMYGPTFLKEVLGFAVNHTGYFVAVP----RALHLAFK 304

  Fly   305 VFADVAMSR-QWMSLTTLRKSINTVSYWGPAAALIGIGFLDKSQTTLA-IALMTI--NAGLNAGS 365
            :.:.||..| |:.|..|..:..||::.....|....:|:|.|.|..|: :||:.|  :.|...|
Worm   305 IISGVASDRIQFWSEKTKMRIFNTIALMVSGAFFCILGYLPKEQAHLSLVALLVIECSTGFICG- 368

  Fly   366 GIGSILTIIDMSPNHSGMLMAIVNGIGNIFPLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFFIG 430
            |.....|::  :..||..:::.:..|..:...:.|||| .::...::..:|:|||....::..:|
Worm   369 GFYKCATLV--ARQHSHFVLSQIQFIKCLSLFIEPLLV-FLICSHNTLEEWRIVFLTHGILLIVG 430

  Fly   431 NLVYLIWGTTDQQAWDAEDYLQAKDPESESNAHQMEFKSRTDSEA 475
            |:::..: .||:.|    |:.::...|..::. ..|.:..|::||
Worm   431 NIIFCYF-ATDEPA----DFTRSATGEEMTDV-PPERRRLTENEA 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	100/461 (22%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	96/443 (22%)
Y15E3A.4	NP_510539.1	MFS	18..438	CDD:391944	96/447 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810