DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and slc-17.7

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_505399.1	Gene:	slc-17.7 / 179308	WormBaseID:	WBGene00022788	Length:	506	Species:	Caenorhabditis elegans

Alignment Length:	482	Identity:	118/482 - (24%)
Similarity:	210/482 - (43%)	Gaps:	64/482 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IRHMQALLLFLAIVVNYTARLSVSVAIV------AMTDA----ATTN------------LDFPEY 54
            :|....:.:.||:.:....|.::::|||      |:||.    |:.|            |.|.|.
Worm    13 VRLRVVIAIALALTIEGLMRSNLNMAIVCMLNSTALTDGKPMIASLNTSIEPATPLCPLLQFGES 77

  Fly    55 N---------WNGVQQSYILSSFYWGYIVTQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTPYCV 110
            .         |....::.|.::||.|.:|....:..|.|..||...:|...:|..|.:.|||:..
Worm    78 KVVEHKGTIFWTSQDRAIIFAAFYAGGLVATLASEVLNRYIGATRSVLYGGIANVVGTFLTPFVA 142

  Fly   111 AWGGWQAF--CTIRIVEGLFQGLIFPCIHEHLAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGL 173
            :...:..|  ..:|.|.|..||:::||:...:|:|.|..:::...|.|.:|.....|:||.::..
Worm   143 SQTNFGTFPIILLRFVMGFGQGVLWPCMLVLIAQWFPVNEKSTALAIATTGNQLSVVIAMFATAE 207

  Fly   174 IANGSMGWPGIFYVSAGTCGL-WCLLWVLFGANNAPSSRLIGSREREHIERSMKRQDGFH---AQ 234
            :.....|||..|:|.| .||: .|::|.:. ..::|.          |.::.:.| |..|   .:
Worm   208 LCQLPWGWPMAFHVYA-VCGIVMCIIWYMM-VYDSPC----------HADKKLSR-DELHYITTE 259

  Fly   235 KIPI-----PWRAIWSSSPFYALLVVRSAQGWANSTMQLQT----PSYMHGVLEMDIKSNALYSA 290
            ::.:     .|.|:..|...:|:    :|..:|::.:.:.|    |.|...||.|.:.||.|:||
Worm   260 RVRLRPQHPNWMALMKSPVVWAI----AASSFAHNYVTVGTITYLPLYYKTVLNMSLTSNGLWSA 320

  Fly   291 LPFLAMWGMSYVYLVFADVAMSRQWMSLTTLRKSINTVSYWGPAAALIGIGFLDKSQTTLAIALM 355
            |||:........|...|:.|..|.|..:..:.|..|:.:.:|.|.....:...|.||...||.|:
Worm   321 LPFVLQLISKVFYAGMAESARKRDWSDINRITKFCNSSASFGIAICFGLLCLCDCSQRGAAIFLI 385

  Fly   356 TINAGLNAGSGIGSILTIIDMSPNHSGMLMAIVNGIGNIFPLLTPLLVGVIVTESDSRSQWQIVF 420
            .:.....:|...|...:.:.::|..:..:.|.....|.|...:.|..:|. .|:..:..:|:|||
Worm   386 CLAMCFVSGYIPGYNTSAVTIAPGQTAAIAAFSRFWGQIASSVAPYHIGA-YTKQGTADEWKIVF 449

  Fly   421 AMTAVVFFIGNLVYLIWGTTDQQAWDA 447
            |:.|.:..:..:.:...||...|.||:
Worm   450 AVIAAICVVTGIFFQCCGTASLQDWDS 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	118/482 (24%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	112/464 (24%)
slc-17.7	NP_505399.1	MFS	31..467	CDD:391944	110/453 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920