DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and slc-17.2

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_499065.1	Gene:	slc-17.2 / 176317	WormBaseID:	WBGene00008000	Length:	493	Species:	Caenorhabditis elegans

Alignment Length:	457	Identity:	121/457 - (26%)
Similarity:	212/457 - (46%)	Gaps:	27/457 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RHMQALLLFLAIVVNYTARLSVSVAIVAM-----TDAATTNLD---------------FPEYNWN 57
            |...:|::|...:|.|..|.::|.|:|.|     ||.....:.               ..|::|:
Worm    15 RFALSLVMFFGCLVTYMMRTNMSFAVVCMVNENKTDTGVEKVSRCGKEMTPVESNSSVIGEFDWD 79

  Fly    58 GVQQSYILSSFYWGYIVTQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTPYCVAWGGWQAFCTIR 122
            ......:||||::|||.:|...|.|..|:|.|.|:.|..|.:|:|:.|.|.......: |...:|
Worm    80 KQTTGMVLSSFFYGYIGSQIIGGHLASRYGGKRVVFVTILGSALLTLLNPVAARTSEY-ALAILR 143

  Fly   123 IVEGLFQGLIFPCIHEHLAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGLIANGSM--GWPGIF 185
            ...|..||..||.:|...:.|.||.:.:.|....|:||..|:|:.:..||.:.....  |||.||
Worm   144 AAIGFLQGATFPAMHTMWSVWGPPLELSVLTGVTYAGAQIGNVIVLPLSGFLCEYGFDGGWPSIF 208

  Fly   186 YVSAGTCG-LWCLLWVLFGANNAPSSRLIGSREREHIERSMKRQDGFHAQKIP-IPWRAIWSSSP 248
            |: .|..| ||..:|....::...:...|...|:::|..:::...|....|:| .||..|.:|..
Worm   209 YI-IGVFGVLWTAVWWYVSSDKPATHPRITPEEKQYIVTAVEASMGKDTGKVPSTPWIKILTSPA 272

  Fly   249 FYALLVVRSAQGWANSTMQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYLVFADVAMSR 313
            .:|......|..|...||.:..||::..||.:::.|....:::|::|.:.......|.||...|:
Worm   273 VWACWAGHFAGDWGAYTMLVSLPSFLKDVLGLNLSSLGAVASIPYIAYFLAINAGGVLADTLRSK 337

  Fly   314 QWMSLTTLRKSINTVSYWGPAAALIGIGFLDKSQTTLAIALMTINAGLNAGSGIGSILTIIDMSP 378
            ..:|....|::...|:..|....|:..|:....|..|.|..:|....::.....|.::..::::|
Worm   338 GILSTLNTRRAAMLVALIGQGIFLVASGYCGCGQDVLVIIFITCGMAISGLQYAGFVVNYLEIAP 402

  Fly   379 NHSGMLMAIVNGIGNIFPLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFFIGNLVYLIWGTTDQQ 443
            ..||.:|...|.|..:..:::| .|...:|.:.::.:||:|..:||.:..||.|::.|:.:.:.|
Worm   403 PFSGTVMGTGNTISALAGIISP-AVSSYLTPNGTQEEWQMVLWLTAGILTIGALLFSIFASGEVQ 466

  Fly   444 AW 445
            .|
Worm   467 PW 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	121/457 (26%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	117/442 (26%)
slc-17.2	NP_499065.1	2A0114euk	4..475	CDD:129972	121/457 (26%)
slc-17.2	NP_499065.1	MFS	70..461	CDD:119392	107/393 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	1	1.010	-	-		D619250at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.930