DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7881 and slc-17.6

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_490947.2	Gene:	slc-17.6 / 171781	WormBaseID:	WBGene00017398	Length:	546	Species:	Caenorhabditis elegans

Alignment Length:	500	Identity:	108/500 - (21%)
Similarity:	204/500 - (40%)	Gaps:	60/500 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 IRHMQALLLFLAIVVNYTARLSVSVAIVAMTDA--ATTNLDFPEYNWNGVQQSYILSSFYWGYIV 74
            ||...|||:..|.||....|....:|:|.:..:  .|.:.|. ...|:|.:|:.|.:|||.|..:
Worm    25 IRFQTALLISAACVVFGLMRTCFGMAMVDIVRSGNGTFHPDL-HMEWSGDEQANIHTSFYIGAFI 88

  Fly    75 TQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTPYCVAW-GGWQAFCTIRIVEGLFQGLIFPCIHE 138
            ..||:.||.::.|.|.:|....|.....|.|||:...: ..:.....||::.|...|.:.|....
Worm    89 AVFPSEFLAKKLGPKNLLSFALLLNIFGSLLTPFSAIYLRSYFPVAAIRLIMGFGYGFVIPAGSV 153

  Fly   139 HLAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGLIANGSM--GWPGIFYVSAGTCGLWCLLWVL 201
            .::.|.|..:::...|...:|...|..::|..:..:.....  |||.:|.|......::.::|.:
Worm   154 LISSWFPLSEKSTAMAIFTTGNQIGIAVSMFLTAKLCQLHFFEGWPLVFIVYGLIGAVFLVIWHV 218

  Fly   202 FGANNAPSSRLIGSREREHIERSMKRQDGFHAQKIPIPWRAIWSSSPFYALLVVRSAQGWANSTM 266
            ..|:....|:.|.:.|..:|:...:|::.........|:..|..:....|:.....||.:....:
Worm   219 RLADKPRESKYITATELTYIKGGKQRRNRAETIVRATPYMKIILNGCVCAICACSFAQSFVLVAL 283

  Fly   267 QLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYLVFADVAMSRQWMSLTTLRKSINTVSYW 331
            ....|.|.....:|::..|.::|:|||........::.:.||....|: ::.|.:.|..|.::.:
Worm   284 VTYLPKYNQIAFKMNLTHNGIWSSLPFFIQMITKLLFAIIADKVKQRK-VNATAVTKVSNAIASF 347

  Fly   332 GPAAALI--GIGFLDKS---QTTLAIALMTINA---GLNAGSGIGSILTIIDMSPNHSGMLMAIV 388
            ..|..::  ..|..|.:   |.::.:::...:|   |.|.        :|:.::|..:..:.:..
Worm   348 ASAIFIVIAAYGPFDSAELVQLSIIVSMAAFSAYVPGYNT--------SIVTVAPQFTAFISSYA 404

  Fly   389 NGIGNIFPLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFFIGNLVYLIWGTTDQQAWDAEDYLQA 453
            .....|...|.|:::|.| |...:..:|:..|...|.|..:..|::.|:|....:.|.
Worm   405 QLYAQIASTLAPIVIGRI-TSHGTIYEWKCAFYSLAGVLAVTGLIFQIFGHGRTEPWG------- 461

  Fly   454 KDPESESNA------------------------HQMEFKSRTDSE 474
               |:.|||                        |..||  ||:|:
Worm   462 ---ETPSNATSARLSTSVTMCEDGMCKLTLLEKHNHEF--RTESK 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	98/449 (22%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	92/431 (21%)
slc-17.6	NP_490947.2	MFS	30..453	CDD:391944	94/433 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	1	1.010	-	-		D619250at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.030