DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and Slc17a1

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	NP_598238.2	Gene:	Slc17a1 / 171080	RGDID:	620099	Length:	465	Species:	Rattus norvegicus

Alignment Length:	455	Identity:	125/455 - (27%)
Similarity:	221/455 - (48%)	Gaps:	31/455 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RHMQALLLFLAIVVNYTARLSVSVAIVAMTDAA-------------TTNLDFPEYNWNGVQQSYI 64
            |:..|:||....:|....|:.:::.:|||.:..             ..|:..|.::|:...|..|
  Rat    17 RYGLAILLHFCNIVIMAQRVCLNLTMVAMVNKTEPPHLSNKSVAEMLDNVKNPVHSWSLDIQGLI 81

  Fly    65 LSSFYWGYIVTQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTPYCVAWGGWQAFCTIRIVEGLFQ 129
            |||.:.|.:|.|.|.|:|...:..|.::......::|||.|.| ..|..|.......|:::|:.|
  Rat    82 LSSVFLGMVVIQVPVGYLSGAYPMKKIIGSSLFLSSVLSLLIP-PAAQVGAALVIVCRVLQGIAQ 145

  Fly   130 GLIFPCIHEHLAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGLIANGSMGWPGIFYVSAGTCGL 194
            |.:....|....||:||.:|.||.:...||...|..:|:..||.|.: .:|||.:||: .|..|
  Rat   146 GAVSTGQHGIWVKWAPPLERGRLTSMTLSGFVMGPFIALLVSGFICD-LLGWPMVFYI-FGIVG- 207

  Fly   195 WCLL---W-VLF--GANNAPSSRLIGSREREHIERSMKRQDGFHAQKIPIPWRAIWSSSPFYALL 253
             |:|   | :||  ..||.|   .:.|.|:::|..|:.:|  .|:.:..:|.:|:..|.|.:|::
  Rat   208 -CVLSLFWFILFFDDPNNHP---YMSSSEKDYITSSLMQQ--VHSGRQSLPIKAMLKSLPLWAII 266

  Fly   254 VVRSAQGWANSTMQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYLVFADVAMSRQWMSL 318
            :...|..|:|:.:...||:::...|.::::.|.|.|:||:|..:....|....:|..:||:..|:
  Rat   267 LNSFAFIWSNNLLVTYTPTFISTTLHVNVRENGLLSSLPYLLAYICGIVAGQMSDFLLSRKIFSV 331

  Fly   319 TTLRKSINTVSYWGPAAALIGIGFLDKSQTTLAIALMTINAGLNAGSGIGSILTIIDMSPNHSGM 383
            ..:||...|:..:.|...::.:.:|..:..:..|.|...|:.|:. |..|.::..:|::|.:.|.
  Rat   332 VAVRKLFTTLGIFCPVIFVVCLLYLSYNFYSTVIFLTLANSTLSF-SFCGQLINALDIAPRYYGF 395

  Fly   384 LMAIVNGIGNIFPLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFFIGNLVYLIWGTTDQQAWDAE 448
            |.|:...||....|::..|.|:|:.: |....|...|.:.|.:.......||::...|.|.|..|
  Rat   396 LKAVTALIGIFGGLISSTLAGLILNQ-DPEYAWHKNFFLMAGINVTCLAFYLLFAKGDIQDWAKE 459

Fly 449 448
Rat 460 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	125/455 (27%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	119/437 (27%)
Slc17a1	NP_598238.2	2A0114euk	1..464	CDD:129972	125/455 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910