DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7881 and slc17a6

DIOPT Version :9

Sequence 1:	NP_001286144.1	Gene:	CG7881 / 35521	FlyBaseID:	FBgn0033048	Length:	482	Species:	Drosophila melanogaster
Sequence 2:	XP_004913390.1	Gene:	slc17a6 / 101730310	XenbaseID:	XB-GENE-1011394	Length:	583	Species:	Xenopus tropicalis

Alignment Length:	462	Identity:	139/462 - (30%)
Similarity:	237/462 - (51%)	Gaps:	31/462 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 RHMQALLLFLAIVVNYTARLSVSVAIVAMTDAATTN------LDFPEYNWNGVQQSYILSSFYWG 71
            |::.|::..|...:::..|.::.||||.|.:.:|.:      .:..::||:......|..||:||
Frog    70 RYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHHGGKIIKEKAKFNWDPEIVGMIHGSFFWG 134

  Fly    72 YIVTQFPAGFLVRRFGAKAVLLVPTLATAVLSGLTPYC--VAWGGWQAFCTI--RIVEGLFQGLI 132
            |||||.|.|::..|..|..|.....:.|:.|:.|.|..  |.:|     |.|  ||::||.:|:.
Frog   135 YIVTQIPGGYIASRLAANRVFGAAIVLTSTLNMLIPSAARVHYG-----CVIFVRILQGLVEGVT 194

  Fly   133 FPCIHEHLAKWSPPEDRNRLGAFAYSGADCGSVLAMASSGLIANGSMGWPGIFYVSAGTCGL-WC 196
            :|..|...:||:||.:|:||...::.|:..|:|:||..:|::...: ||..:||| .|..|| |.
Frog   195 YPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYT-GWSSVFYV-YGCFGLVWY 257

  Fly   197 LLWVLFGANNAPSSRLIGSREREHIERSMKRQDGF--HAQKIPIPWRAIWSSSPFYALLVVRSAQ 259
            |.|:|....:......|...||.:||.|:......  ..:|...|||..::|.|.||::|....:
Frog   258 LFWILVSYESPAKHPTITDEERNYIEESIGESANILGPVEKFKTPWRKFFTSMPVYAIIVANFCR 322

  Fly   260 GWANSTMQLQTPSYMHGVLEMDIKSNALYSALPFLAMWGMSYVYLVFADVAMSRQWMSLTTLRKS 324
            .|....:.:..|:|...|...:|....:.||:|.|.|..:..:....||...|:|.:|.||:||.
Frog   323 SWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKI 387

  Fly   325 INTVSYWGPAAALIGIGFLDKSQTTLAIALMTINAGLNAGSGIGSILTIIDMSPNHSGMLMAIVN 389
            :|...:...|..|:.:|:  .....:||:.:.:..|.:..:..|..:..:|::|.::.:||.|.|
Frog   388 MNCGGFGMEATLLLVVGY--SHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISN 450

  Fly   390 GIGNIFPLLTPLLVGVIVTESDSRSQWQIVFAMTAVVFFIGNLVYLIWGTTDQQAWDAEDYLQAK 454
            |:|.:..::.||:||. :|:..||.:||.||.:.|:|.:.|.:.|.|:.:.::|.|        .
Frog   451 GVGTLSGMVCPLIVGA-MTKHKSREEWQYVFLIAALVHYGGVIFYGIFASGEKQPW--------A 506

  Fly   455 DPESESN 461
            |||..|:
Frog   507 DPEQTSD 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7881	NP_001286144.1	2A0114euk	12..449	CDD:129972	135/448 (30%)
CG7881	NP_001286144.1	MFS	18..437	CDD:119392	130/431 (30%)
slc17a6	XP_004913390.1	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	132/433 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000