DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7882 and HXT2

DIOPT Version :9

Sequence 1:	NP_610189.2	Gene:	CG7882 / 35520	FlyBaseID:	FBgn0033047	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_013724.1	Gene:	HXT2 / 855023	SGDID:	S000004613	Length:	541	Species:	Saccharomyces cerevisiae

Alignment Length:	551	Identity:	125/551 - (22%)
Similarity:	211/551 - (38%)	Gaps:	109/551 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 QSLTFSEAPLMAHENGKQEERPQWSWSLNWAAIGSSL----GAAVPVGYCTGVMN---SPAELMR 70
            |.|...|:|:.........|.|....:..|..|...|    |..| .|:.||.::   :..:..|
Yeast    25 QKLETDESPIQTKSEYTNAELPAKPIAAYWTVICLCLMIAFGGFV-FGWDTGTISGFVNQTDFKR 88

  Fly    71 SWCNETLIASYDLNLSDAGLEILWSAIVSIFLVGGAIGSVVGATMANRFGRR---GC---FFICG 129
            .:.......:|.|:....||      ||.||.:|.|.|.:....:.:.:|||   .|   .:|.|
Yeast    89 RFGQMKSDGTYYLSDVRTGL------IVGIFNIGCAFGGLTLGRLGDMYGRRIGLMCVVLVYIVG 147

  Fly   130 LLLGLGAI-SFYACRPLRSVELLLLGRMMVGLAGGLLTSFMSMWHSEISALSQRSTLAPLCPMGL 193
            :::.:.:. .:|.         ..:||::.|:..|.:........||.:....|.|......:.:
Yeast   148 IVIQIASSDKWYQ---------YFIGRIISGMGVGGIAVLSPTLISETAPKHIRGTCVSFYQLMI 203

  Fly   194 TLGVVIAQVCSL------RSVLGGPENWHFGLAFYGLLVLVCYAPFRWYPESPKWLFIVQGRKED 252
            |||:.:....:.      .||     .|...|.......:...|.....||||::| :.:||.||
Yeast   204 TLGIFLGYCTNYGTKDYSNSV-----QWRVPLGLNFAFAIFMIAGMLMVPESPRFL-VEKGRYED 262

  Fly   253 ARRQLQLLRGYTAGSAALKAEMEEMEQESACEVKTSSLM------QVLRDPQLRLPLIIVCAFLG 311
            |:|.|......|....::.|||:.:    ...|:|..|.      ::..:....||.:|:...:.
Yeast   263 AKRSLAKSNKVTIEDPSIVAEMDTI----MANVETERLAGNASWGELFSNKGAILPRVIMGIMIQ 323

  Fly   312 G-QQLSGINAIFYYSVSIFRKAGLSSQASEWANLGAGSLNLFASMLGPVLLERVNRRPLMLFSTF 375
            . |||:|.|..|||..:||...|:..  |...::..|.:|..::.:....:::..||..:|..:.
Yeast   324 SLQQLTGNNYFFYYGTTIFNAVGMKD--SFQTSIVLGIVNFASTFVALYTVDKFGRRKCLLGGSA 386

  Fly   376 FCAVFLLLFA----------------------IMLFFIESYSWFGMGCIGCIFLYIFFFQFGLGP 418
            ..|:..::|:                      :|:.|.            |:|  ||||.....|
Yeast   387 SMAICFVIFSTVGVTSLYPNGKDQPSSKAAGNVMIVFT------------CLF--IFFFAISWAP 437

  Fly   419 MPFFIGAELFELATRPAAMSLGSLAYWLCNFIIGMAFPTMQN---------LWGALVFLPFSVTC 474
            :.:.|.||.:.|..:..||::...|.|:..|:||...|.:.:         ..|.|||..|.|
Yeast   438 IAYVIVAESYPLRVKNRAMAIAVGANWIWGFLIGFFTPFITSAIGFSYGYVFMGCLVFSFFYV-- 500

  Fly   475 LLIFGLTKRYLPETRGRHPSEVAPLVALGFK 505
              .|     ::.||:|....||..:...|.|
Yeast   501 --FF-----FVCETKGLTLEEVNEMYVEGVK 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7882	NP_610189.2	Sugar_tr	43..491	CDD:278511	113/505 (22%)
CG7882	NP_610189.2	MFS	95..480	CDD:119392	99/435 (23%)
HXT2	NP_013724.1	Sugar_tr	59..519	CDD:395036	115/510 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342896
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13429
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840