DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7882 and MAL11

DIOPT Version :9

Sequence 1:	NP_610189.2	Gene:	CG7882 / 35520	FlyBaseID:	FBgn0033047	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_011805.3	Gene:	MAL11 / 853207	SGDID:	S000003521	Length:	616	Species:	Saccharomyces cerevisiae

Alignment Length:	553	Identity:	129/553 - (23%)
Similarity:	205/553 - (37%)	Gaps:	111/553 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 QEQSLTFSEAPLMAHENGKQEERPQWSWSLNWAAIGSSLGAAVPVGYCTGVMNSPAEL---MRSW 72
            :|:|:|..:|.|      |..:...||     ..:.::|   |..||.|.::::...|   .|.:
Yeast    90 EEKSMTLKQALL------KYPKAALWS-----ILVSTTL---VMEGYDTALLSALYALPVFQRKF 140

  Fly    73 CNETLIASYDLNLS-DAGLEILWSAIVSIFLVGGAIGSVVGATMANRFGRRGCFFIC-GLLLGLG 135
            .......||::... ..||.:       ..|.|..||..:...|....|.|...... |||....
Yeast   141 GTLNGEGSYEITSQWQIGLNM-------CVLCGEMIGLQITTYMVEFMGNRYTMITALGLLTAYI 198

  Fly   136 AISFYACRPLRSVELLLLGRMMVGLAGGLLTSFMSMWHSEISALSQRSTLAPLCPMGLTLGVV-I 199
            .|.:|.    :|:.::.:|:::..:..|...|....:.||:            ||:.|...:. .
Yeast   199 FILYYC----KSLAMIAVGQILSAIPWGCFQSLAVTYASEV------------CPLALRYYMTSY 247

  Fly   200 AQVCSLRSVLGGPENWHFGLAF-----------YGLLVLVCYAPF--RWY------------PES 239
            :.:|           |.||..|           .|...|....||  :|.            |||
Yeast   248 SNIC-----------WLFGQIFASGIMKNSQENLGNSDLGYKLPFALQWIWPAPLMIGIFFAPES 301

  Fly   240 PKWLFIVQGRKEDARRQL-QLLRGYTAG-----SAALKAEMEEMEQESACEVKTSSLMQVLRDPQ 298
            |.|| :.:.|..:||:.| ::|.|..|.     ...||.....:|:|.....|:.|.....:...
Yeast   302 PWWL-VRKDRVAEARKSLSRILSGKGAEKDIQVDLTLKQIELTIEKERLLASKSGSFFNCFKGVN 365

  Fly   299 LRLPLIIVCAFLGGQQLSGINAIFYYSVSIFRKAGLSSQASEWANLGAGSLNLFASMLGPVLLER 363
            .|... :.|.....|..||. .:..||...|.:||:::..:...:|....|.|..::...|:..|
Yeast   366 GRRTR-LACLTWVAQNSSGA-VLLGYSTYFFERAGMATDKAFTFSLIQYCLGLAGTLCSWVISGR 428

  Fly   364 VNRRPLMLFSTFFCAVFLLLFAIMLFFIESYSWFGMGCIGCIFLYIFFFQFGLGPMPFFIGAELF 428
            |.|..::.:...|..|.|.:...|.|...|.:..|.|  |.:....||:..|:|.:.:.|.||:.
Yeast   429 VGRWTILTYGLAFQMVCLFIIGGMGFGSGSSASNGAG--GLLLALSFFYNAGIGAVVYCIVAEIP 491

  Fly   429 ELATRPAAMSLGSLAYWLCNFIIGMAFPTMQNL----WGALV------FLPFSVTCLLIFGLTKR 483
            ....|...:.|..:.|.|...|..:..|.|.|:    |||..      |...::..::|
Yeast   492 SAELRTKTIVLARICYNLMAVINAILTPYMLNVSDWNWGAKTGLYWGGFTAVTLAWVII------ 550

  Fly   484 YLPETRGRHPSEVAPLVALG-----FKSKVMLP 511
            .||||.||..||:..|...|     |.|.|:.|
Yeast   551 DLPETTGRTFSEINELFNQGVPARKFASTVVDP 583

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7882	NP_610189.2	Sugar_tr	43..491	CDD:278511	111/494 (22%)
CG7882	NP_610189.2	MFS	95..480	CDD:119392	96/427 (22%)
MAL11	NP_011805.3	SP	81..563	CDD:273317	122/531 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342812
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840