DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7882 and ITR1

DIOPT Version :9

Sequence 1:	NP_610189.2	Gene:	CG7882 / 35520	FlyBaseID:	FBgn0033047	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_010785.1	Gene:	ITR1 / 852108	SGDID:	S000002905	Length:	584	Species:	Saccharomyces cerevisiae

Alignment Length:	501	Identity:	116/501 - (23%)
Similarity:	216/501 - (43%)	Gaps:	82/501 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 GYCTGVMNSPAELMRSWCNETLIA---SYDLNLSDAGLEILWSAIVSIFLVGGAIGSVVGATMAN 117
            ||.||.::|           .||:   ..|..:...|.:.:.:|..|:   |..|.|:...|.|:
Yeast   101 GYDTGYISS-----------ALISIGTDLDHKVLTYGEKEIVTAATSL---GALITSIFAGTAAD 151

  Fly   118 RFGRRGC------FFICGLLLGLGAISFYACRPLRSVELLLLGRMMVGLAGGLLTSFMSMWHSEI 176
            .|||:.|      .|:.|.:|.:.|.:|:.         :.:||:::|...|:.:....::.|||
Yeast   152 IFGRKRCLMGSNLMFVIGAILQVSAHTFWQ---------MAVGRLIMGFGVGIGSLIAPLFISEI 207

  Fly   177 SALSQRSTLAPLCPMGLTLGVVIAQVC--SLRSVLGGPENWHF--GLAFYGLLV---LVCYAPFR 234
            :....|..|..:..:.||.|.::|..|  .|..|..|   |..  ||:.....|   .:|:
Yeast   208 APKMIRGRLTVINSLWLTGGQLVAYGCGAGLNYVNNG---WRILVGLSLIPTAVQFTCLCF---- 265

  Fly   235 WYPESPKWLFIVQGRKEDARRQLQLL-RGYT-AGSAALKAEMEEM-------EQESACEVKTSSL 290
             .|::|:: ::::|   |..|..::| |.|| .....::.::||:       ..::..|...:::
Yeast   266 -LPDTPRY-YVMKG---DLARATEVLKRSYTDTSEEIIERKVEELVTLNQSIPGKNVPEKVWNTI 325

  Fly   291 MQVLRDPQLRLPLIIVCAFLGGQQLSGINAIFYYSVSIFRKAGLSSQASEWANLGAGSLNLFASM 355
            .::...|.....|||.|.....||.:|.|::.|:|.:||...|..:.::  .::.....|...::
Yeast   326 KELHTVPSNLRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKNSSA--VSIIVSGTNFIFTL 388

  Fly   356 LGPVLLERVNRRPLMLFSTFFCAVFLLLFAIMLFFI-------------ESYSWFGMGCIGCIFL 407
            :....::::.||.::|.......:.|::.:|...|:             ..:|.:|:..|..|.:
Yeast   389 VAFFSIDKIGRRTILLIGLPGMTMALVVCSIAFHFLGIKFDGAVAVVVSSGFSSWGIVIIVFIIV 453

  Fly   408 YIFFFQFGLGPMPFFIGAELFELATRPAAMSLGSLAYWLCNFIIGMAFPTM-QNLWGALVFLPFS 471
            :..|:..|:|.:| :..:|||....|....|..:...|..:.:|...|.|| ||:..|..|..|:
Yeast   454 FAAFYALGIGTVP-WQQSELFPQNVRGIGTSYATATNWAGSLVIASTFLTMLQNITPAGTFAFFA 517

  Fly   472 -VTCLLIFGLTKRYLPETRGRHPSEVAPLVALGFK---SKVMLPKQ 513
             ::||........| ||..|....||..::..||.   ||.:..|:
Yeast   518 GLSCLSTIFCYFCY-PELSGLELEEVQTILKDGFNIKASKALAKKR 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7882	NP_610189.2	Sugar_tr	43..491	CDD:278511	108/474 (23%)
CG7882	NP_610189.2	MFS	95..480	CDD:119392	96/421 (23%)
ITR1	NP_010785.1	MFS_HMIT_like	92..533	CDD:340918	106/470 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342421
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840