DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7882 and HXT7

DIOPT Version :9

Sequence 1:	NP_610189.2	Gene:	CG7882 / 35520	FlyBaseID:	FBgn0033047	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_010629.3	Gene:	HXT7 / 851943	SGDID:	S000002750	Length:	570	Species:	Saccharomyces cerevisiae

Alignment Length:	549	Identity:	135/549 - (24%)
Similarity:	236/549 - (42%)	Gaps:	104/549 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LMAHENGKQEE-------RPQWSW-SLNWAAIGSSLGAAVPVGYCTGVMNSPAELMRSWCNET-L 77
            :.|:..|::.|       ||..:: :::...|..:.|..| .|:.||.::       .:.|:| .
Yeast    39 IKAYGEGEEHEPVVEIPKRPASAYVTVSIMCIMIAFGGFV-FGWDTGTIS-------GFINQTDF 95

  Fly    78 IASYDLNLSDAG---LEILWSAIVSIFLVGGAIGSVVGATMANRFGRR------GCFFICGLLLG 133
            |..:.:...|..   .::....|||||.:|.|||.::.:.:.:.:||:      ...:|.|:::.
Yeast    96 IRRFGMKHKDGTNYLSKVRTGLIVSIFNIGCAIGGIILSKLGDMYGRKVGLIVVVVIYIIGIIIQ 160

  Fly   134 LGAIS-FYACRPLRSVELLLLGRMMVGLAGGLLTSFMSMWHSEISALSQRSTLAPLCPMGLTLGV 197
            :.:|: :|.         ..:||::.||..|.:.....|..||:|....|.||.....:.:|.|:
Yeast   161 IASINKWYQ---------YFIGRIISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMITAGI 216

  Fly   198 VIAQVCSLRSVLGGPEN------WH--FGLAFYGLLVLVCYAPFRWYPESPKWLFIVQGRKEDAR 254
            .:....:.     |.:|      |.  .||.|...|.::  ....:.||||::|..| |:.|:|:
Yeast   217 FLGYCTNF-----GTKNYSNSVQWRVPLGLCFAWALFMI--GGMTFVPESPRYLAEV-GKIEEAK 273

  Fly   255 RQLQLLRGYTAGSAALKAEMEE----MEQESACEVKT-----SSLMQVLRDPQLRLPLIIVCAFL 310
            |.:.:.........::.||:|.    :|.|......:     ||..:||:      .||:.....
Yeast   274 RSIAVSNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFSSKTKVLQ------RLIMGAMIQ 332

  Fly   311 GGQQLSGINAIFYYSVSIFRKAGLSSQASEWANLGAGSLNLFASMLGPVLLERVNRRPLMLFSTF 375
            ..|||:|.|..|||..:||:..|||.  |...::..|.:|..::.:|..::||..||..:|:...
Yeast   333 SLQQLTGDNYFFYYGTTIFKAVGLSD--SFETSIVLGIVNFASTFVGIYVVERYGRRTCLLWGAA 395

  Fly   376 FCAVFLLLFAIMLFFIESYSW-------FGMGCIGCIFL----YIFFFQFGLGPMPFFIGAELFE 429
            .....::::|.:..   :..|       ...|...|:.:    |||.|.....|:|:.:.:|.|.
Yeast   396 SMTACMVVYASVGV---TRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPIPYVVVSETFP 457

  Fly   430 LATRPAAMSLGSLAYWLCNFIIGMAFPTMQN---------LWGALVFLPFSVTCLLIFGLTKRYL 485
            |..:..|||:.:.|.||..|:||...|.:..         ..|.|||:.|.|  ||:       :
Yeast   458 LRVKSKAMSIATAANWLWGFLIGFFTPFITGAINFYYGYVFMGCLVFMFFYV--LLV-------V 513

  Fly   486 PETRGRHPSEVAPL---VALGFKSKVMLP 511
            |||:|....||..:   ..|.:||...:|
Yeast   514 PETKGLTLEEVNTMWEEGVLPWKSASWVP 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7882	NP_610189.2	Sugar_tr	43..491	CDD:278511	123/495 (25%)
CG7882	NP_610189.2	MFS	95..480	CDD:119392	110/428 (26%)
HXT7	NP_010629.3	Sugar_tr	68..528	CDD:395036	126/504 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342902
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4260
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13429
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.790