Protein Alignment CG7882 and SPNS1

DIOPT Version :10

• Sequence 1: NP_610189.2
• Gene: CG7882 / 35520
• FlyBaseID: FBgn0033047
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: XP_047290695.1
• Gene: SPNS1 / 83985
• HGNCID: 30621
• Length: 586
• Species: Homo sapiens
• Alignment Length: 493
• Identity: 107/493 - (21%)
• Similarity: 175/493 - (35%)
• Gaps: 127/493 - (25%)

  Fly    84 NLSDAGLEILWSAIVSIFLVGGAIGSVVGATMANRFGRRGCFFICG-----LLLGLGAISFYACR 143
            |:.|:...::.:..:|.::|...:...:|    :|:.|:  :.:||     .|:.||: ||.
Human   136 NIGDSSSGLIQTVFISSYMVLAPVFGYLG----DRYNRK--YLMCGGIAFWSLVTLGS-SFI--- 190

  Fly   144 PLRSVELLLLGRMMVGLAGGLLTSFMSMWHSEISALSQRSTLAPL----CPMGLTLGVVIAQVCS 204
            |.....||||.|.:||:.....::......:::....|||.:..:    .|:|..||.:...  .
Human   191 PGEHFWLLLLTRGLVGVGEASYSTIAPTLIADLFVADQRSRMLSIFYFAIPVGSGLGYIAGS--K 253

  Fly   205 LRSVLGGPENWHFGLAFY-GLLVLVCYAPFRWYPESPKWLFIVQGRKEDARRQLQLLRGYTAGSA 268
            ::.:.|   :||:.|... ||.|:.....|....|.|:                        |:.
Human   254 VKDMAG---DWHWALRVTPGLGVVAVLLLFLVVREPPR------------------------GAV 291

  Fly   269 ALKAEMEEMEQESACEVKTSSLMQVLRDPQLRLPLI--IVCAFLGGQQLSGINAIFYYSVSIFRK 331
            ...:::..:...|    ..:.|..:.|:|...|..:  ...||:.|.......|....|..:..:
Human   292 ERHSDLPPLNPTS----WWADLRALARNPSFVLSSLGFTAVAFVTGSLALWAPAFLLRSRVVLGE 352

  Fly   332 A-----GLSSQASEWANLGAGSLNLFASMLGPVLLERVNRR---------PLMLFSTFFCAVFLL 382
            .     |.|..:|:  :|..|.:.....:||..|...::||         ||:      ||..||
Human   353 TPPCLPGDSCSSSD--SLIFGLITCLTGVLGVGLGVEISRRLRHSNPRADPLV------CATGLL 409

  Fly   383 LFAIMLFFIESYSWFGMGCI--GCIFLYIFFFQFG--LGPMPFFIGAELFELATRPAAMSLGS-- 441
            ..|..||       ..:.|.  ..:..|||.| .|  |..|.:.|.|::......|...|...
Human   410 GSAPFLF-------LSLACARGSIVATYIFIF-IGETLLSMNWAIVADILLYVVIPTRRSTAEAF 466

  Fly   442 ---LAYWLCN----FIIGMAFPTMQ-----NLW----GALVFLPFSV--------TCLLI----- 477
               |::.|.:    ::||:|..|.|     .||    .|....|:.|        |.|.|
Human   467 QIVLSHLLGDAGSPYLIGLACCTKQGPQTTGLWCPSGAAPPACPWPVCSSERLPLTYLHICHSWP 531

  Fly   478 -------FGLTKRYLPETRGRHPSEVAPLVALGFKSKV 508
                   .|||....|.:||......||...||....|
Human   532 WAHPTKGLGLTPWPGPASRGTLGRVPAPRHYLGLLKTV 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7882	NP_610189.2	MFS_GLUT_Class1_2_like	44..491	CDD:340915	101/474 (21%)
SPNS1	XP_047290695.1	MFS_spinster_like	107..499	CDD:340886	88/421 (21%)