DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7882 and slc2a1a

DIOPT Version :9

Sequence 1:	NP_610189.2	Gene:	CG7882 / 35520	FlyBaseID:	FBgn0033047	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001034897.1	Gene:	slc2a1a / 555778	ZFINID:	ZDB-GENE-030131-3158	Length:	488	Species:	Danio rerio

Alignment Length:	475	Identity:	172/475 - (36%)
Similarity:	255/475 - (53%)	Gaps:	17/475 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ENGKQEERPQWSWSLNWAAIGSSLGAAVPVGYCTGVMNSPAELMRSWCNETLIASYDLNLSDAGL 90
            |:.|:|..||...::..|.|||     :..||.|||:|:|.:::..:.|||....|...:....|
Zfish     2 ESNKKEVTPQLMMAVGTAVIGS-----LQFGYNTGVINAPQKIIEGFYNETWHNRYSEYIPPTTL 61

  Fly    91 EILWSAIVSIFLVGGAIGSVVGATMANRFGRRGCFFICGLLLGLGAISFYACRPLRSVELLLLGR 155
            ..|||..|:||.|||.:||.......||||||....|..:|..:.|......:...|.|:|::||
Zfish    62 TTLWSVSVAIFSVGGILGSFSVGLFVNRFGRRNSMLIANILAFIAAAFMGFSKLAESWEMLIIGR 126

  Fly   156 MMVGLAGGLLTSFMSMWHSEISALSQRSTLAPLCPMGLTLGVVIAQVCSLRSVLGGPENWHFGLA 220
            .:|||..||.|.|:.|:..||:..|.|..|..|..:|:.:|:::||:..::.::|.|..|.|.|.
Zfish   127 FIVGLYSGLSTGFVPMYVGEIAPTSLRGALGTLHQLGIVIGILMAQIFGIKEIMGSPTLWPFMLG 191

  Fly   221 FYGL-LVLVC-YAPFRWYPESPKWLFIVQGRKEDARRQLQLLRGYTAGSAALKAEMEEMEQES-- 281
            |..: .||.| ..||  .||||::|.|.|..:..|:..|:.||    |:..:.|:|:||..||
Zfish   192 FTFIPAVLQCALLPF--CPESPRYLLINQNEEAKAKSVLKKLR----GTDDVGADMQEMRDESRQ 250

  Fly   282 ACEVKTSSLMQVLRDPQLRLPLIIVCAFLGGQQLSGINAIFYYSVSIFRKAGLSSQASEWANLGA 346
            ....||.::.::.|....|.|:.|.......||.|||||:||||..||.|||:|...  :|.:||
Zfish   251 MMREKTVTIPELFRSSLYRQPIFIAIMLQLSQQFSGINAVFYYSTGIFEKAGVSEPV--YATIGA 313

  Fly   347 GSLNLFASMLGPVLLERVNRRPLMLFSTFFCAVFLLLFAIMLFFIESYSWFGMGCIGCIFLYIFF 411
            |::|...:::...::|||.||.|.|......||..:|..|.:..:....|.....|..||.::.|
Zfish   314 GAVNTAFTVVSLFIVERVGRRSLHLVGLMGMAVSSVLMTIAMALLTKVEWMSYVSIVAIFSFVAF 378

  Fly   412 FQFGLGPMPFFIGAELFELATRPAAMSLGSLAYWLCNFIIGMAFPTMQNLWGALVFLPFSVTCLL 476
            |:.|.||:|:||.||||....||:|.::...:.|..||::||.|..::.|.|..||:.|:|..|:
Zfish   379 FEIGPGPIPWFIVAELFSQGPRPSAFAVAGFSNWFANFLVGMCFQYVEELTGPYVFIIFTVLLLI 443

  Fly   477 IFGLTKRYLPETRGRHPSEV 496
            .|..|...:|||:||...|:
Zfish   444 FFVFTYFKVPETKGRSFEEI 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7882	NP_610189.2	Sugar_tr	43..491	CDD:278511	164/451 (36%)
CG7882	NP_610189.2	MFS	95..480	CDD:119392	142/388 (37%)
slc2a1a	NP_001034897.1	Sugar_tr	18..467	CDD:278511	167/459 (36%)
slc2a1a	NP_001034897.1	MFS	62..450	CDD:119392	145/395 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577180
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2574
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23503
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.900