DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7882 and Slc2a9

DIOPT Version :9

Sequence 1:	NP_610189.2	Gene:	CG7882 / 35520	FlyBaseID:	FBgn0033047	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001178480.1	Gene:	Slc2a9 / 501925	RGDID:	1597012	Length:	545	Species:	Rattus norvegicus

Alignment Length:	489	Identity:	149/489 - (30%)
Similarity:	243/489 - (49%)	Gaps:	28/489 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 GKQEERPQ----WSWSLNWAAIGSSLGAAVPVGYCTGVMNSPAELMRSWCNETLIASYDLNLSDA 88
            |::..||:    ||.||..||:..:.|::...||...|:|:|...::::.|||....:...:...
  Rat    28 GRRGWRPRRTKNWSCSLIVAALVGAFGSSFLYGYNLSVVNAPTPYIKAFYNETWYRRHGQPIDPD 92

  Fly    89 GLEILWSAIVSIFLVGGAIGSVVGATMANRFGRRGCFFICGLLLGLG-AIS---FYACR-PLRSV 148
            .|.:|||..||||.:||.:|:::...:....||:     ..||:..| |||   ..||. ...:.
  Rat    93 TLTLLWSVTVSIFAIGGLVGTLMVKMIGKFLGRK-----YTLLVNNGFAISAALLMACSLQAGTF 152

  Fly   149 ELLLLGRMMVGLAGGLLTSFMSMWHSEISALSQRSTLAPLCPMGLTLGVVIAQVCSLRSVLGGPE 213
            |:|::||.::|:.||:..|.:.|:.:|||....|.:|..:..:.:.:||...|:..|..:||...
  Rat   153 EMLIVGRFIMGVDGGIALSALPMYLNEISPKEIRGSLGQVTAIFICIGVFSGQLLGLPELLGKER 217

  Fly   214 NWH--FGLAFYGLLVLVCYAPFRWYPESPKWLFIVQGRKEDARRQLQLLRGYTAGSAALKAEMEE 276
            .|.  ||:.....|..:...||  .||||::|...:..:..|.:..|..    .|.|.:..|:||
  Rat   218 TWPYLFGVIIVPALAQLASLPF--LPESPRYLLFEKHDEAGATKAFQTF----LGKADVSQELEE 276

  Fly   277 MEQESACE--VKTSSLMQVLRDPQLRLPLIIVCAFLGGQQLSGINAIFYYSVSIFRKAGLSSQAS 339
            ...||..:  ::..|:.::||.|.:|..:|.|...:...||.|:|||::|:.|||.|||:.....
  Rat   277 ALAESRVQRNLRLVSVFELLRAPFVRWQVITVVITMASYQLCGLNAIWFYTNSIFGKAGVPQDKI 341

  Fly   340 EWANLGAGSLNLFASMLGPVLLERVNRRPLMLFSTFFCAVFLLLFAIMLFFIESYSWFGMGCIGC 404
            .:..|..|.:...|::...:::||:.||||::......|:|..:..:.|...:...|.....|.|
  Rat   342 PYITLSTGGIETLAAIFSGLVIERLGRRPLLIGGFGLMALFFGMLTVTLTLQDQAPWIPYLSIVC 406

  Fly   405 IFLYIFFFQFGLGPMPFFIGAELFELATRPAAMSLGSLAYWLCNFIIGMAFPTMQNLWGALVFLP 469
            |...|..|..|.|.:||.:..|.|:.:.||||..:.....||.||::|:.||.:|....:..||.
  Rat   407 ILAIIASFCSGPGGIPFILTGEFFQQSERPAAFIIAGTVNWLSNFVVGLLFPFIQKSLESYCFLV 471

  Fly   470 FSVTCLLIFGLTKRY--LPETRGRHPSEVAPLVA 501
            |:..|  |.|....|  ||||:.|..:|::...|
  Rat   472 FATIC--IAGAIYFYFVLPETKNRTHAEISQAFA 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7882	NP_610189.2	Sugar_tr	43..491	CDD:278511	139/458 (30%)
CG7882	NP_610189.2	MFS	95..480	CDD:119392	119/393 (30%)
Slc2a9	NP_001178480.1	Sugar_tr	47..502	CDD:278511	141/467 (30%)
Slc2a9	NP_001178480.1	MFS	49..486	CDD:119392	133/449 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338003
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	321	0.113	Inparanoid score	I2429
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.800