DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7882 and slc2a2

DIOPT Version :9

Sequence 1:	NP_610189.2	Gene:	CG7882 / 35520	FlyBaseID:	FBgn0033047	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001036186.1	Gene:	slc2a2 / 322493	ZFINID:	ZDB-GENE-030131-1213	Length:	504	Species:	Danio rerio

Alignment Length:	500	Identity:	166/500 - (33%)
Similarity:	265/500 - (53%)	Gaps:	66/500 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 QWSWSLNWAAIGSSLGAAVPVGYCTGVMNSPAELM-RSWCNETLIASYDLNLSDAG--------- 89
            |.:.:|..|...::|| ::.:||..||:|:|.::: |.:.....:.:.||..|:.|
Zfish     4 QLTGTLALAVFTAALG-SLQMGYSLGVINAPQKVIERHYARSLGVYNEDLARSEGGNGTEHEKPT 67

  Fly    90 ---LEILWSAIVSIFLVGGAIGSVVGATMANRFGR-RGCFFI------CGLLLGLGAISFYACRP 144
               :.:.||..|:||.|||.:.|.:.:.:.:..|| :|...|      .|||:||..:.
Zfish    68 DPSVVMYWSLSVAIFSVGGMLSSFLVSFVGDFRGRIKGMLAINVLAITAGLLMGLAKMG------ 126

  Fly   145 LRSVELLLL-GRMMVGLAGGLLTSFMSMWHSEISALSQRSTLAPLCPMGLTLGVVIAQVCSLRSV 208
              :..|::: ||.::||..||.:..:.::..|||.:..|..:..|..:.:.:|::|:||..|..:
Zfish   127 --TPHLMVIAGRAIMGLYCGLSSGLVPLYIGEISPVKYRGAMGALHQLAIVIGILISQVIGLDFL 189

  Fly   209 LGGPENWHFGLAFYG-------LLVLVCYAPFRWYPESPKWLFIVQGRKEDARRQLQLLRG-YTA 265
            ||....||..|...|       ||:|||       ||||::|:|.||:.|||.:.|:.|:| |..
Zfish   190 LGNDYMWHILLGLSGAPAILQSLLLLVC-------PESPRYLYIKQGKVEDACKSLKRLKGDYDT 247

  Fly   266 GS--AALKAEMEEMEQESACEVKTSSLMQVLRDPQLRLPLIIVCAFLGGQQLSGINAIFYYSVSI 328
            ..  |.:|||.||..:|:     ..|::::||....|..|.:.......||.||||||||||.||
Zfish   248 SKDIAEMKAEKEEAMKEA-----KMSILRLLRSSVYRQQLFVALMMHFSQQFSGINAIFYYSTSI 307

  Fly   329 FRKAGLSSQASEWANLGAGSLNLFASMLGPVLLERVNRRPLMLF---STFFCAVFLLLFAIMLFF 390
            |:.||:....  :|.:|.|.:|:..:::..::::|..||.|.|.   ....|||.:   .:.|.|
Zfish   308 FQTAGVGQPV--YATIGVGVVNIIFTLVSVLMVDRAGRRTLTLVGLGGMCCCAVAM---TVGLAF 367

  Fly   391 IESYSWFGMGCIGCIFLYIFFFQFGLGPMPFFIGAELFELATRPAAMSLGSLAYWLCNFIIGMAF 455
            ..:|||.....:..||:::.||:.|.||:|:||.||:|....||||::|.....|.||||:||.|
Zfish   368 QGAYSWMSYVSMVAIFMFVSFFEIGPGPIPWFIVAEIFSQGPRPAAIALAGFCNWTCNFIVGMVF 432

  Fly   456 PTMQNLWGALVFLPFSVTCLLIFGLTKRY---LPETRGRHPSEVA 497
            |.:.:|.|:.||:.|:|   |:||.|...   :|||:|:...|:|
Zfish   433 PYLVSLCGSYVFIVFAV---LLFGFTLFIYFRVPETKGKTFEEIA 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7882	NP_610189.2	Sugar_tr	43..491	CDD:278511	161/484 (33%)
CG7882	NP_610189.2	MFS	95..480	CDD:119392	141/405 (35%)
slc2a2	NP_001036186.1	Sugar_tr	12..477	CDD:278511	163/491 (33%)
slc2a2	NP_001036186.1	MFS	76..462	CDD:119392	143/413 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577206
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	311	1.000	Inparanoid score	I2574
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23503
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.900