DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7882 and Slc2a3

DIOPT Version :9

Sequence 1:	NP_610189.2	Gene:	CG7882 / 35520	FlyBaseID:	FBgn0033047	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	XP_006237357.1	Gene:	Slc2a3 / 25551	RGDID:	3706	Length:	495	Species:	Rattus norvegicus

Alignment Length:	472	Identity:	167/472 - (35%)
Similarity:	249/472 - (52%)	Gaps:	21/472 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ENGKQEERPQWSWSLNWAAIGSSLGAAVPVGYCTGVMNSPAELMRSWCNETLIASYDLNLSDAGL 90
            |:.||...|...:::..|.|||     ...||.|||:|:|..:::.:.|.||....:...|:..|
  Rat     2 ESNKQNVTPSLVFAVTVATIGS-----FQFGYNTGVINAPETIIKDFLNYTLEERLEDLPSEGLL 61

  Fly    91 EILWSAIVSIFLVGGAIGSVVGATMANRFGRRGCFFICGLLLGLGAISFYACRPLRSVELLLLGR 155
            ..|||..|:||.|||.|||.......||||||....:..|:..||.......:...|||:|:|||
  Rat    62 TTLWSLCVAIFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLIAILGGCLMGFAKIAESVEMLILGR 126

  Fly   156 MMVGLAGGLLTSFMSMWHSEISALSQRSTLAPLCPMGLTLGVVIAQVCSLRSVLGGPENWH--FG 218
            :::|:..||.|.|:.|:..|:|..:.|.....|..:|:.:|:::|||..|..:||..|.|.  .|
  Rat   127 LIIGIFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQVFGLDFILGSEELWPGLLG 191

  Fly   219 LAFYGLLVLVCYAPFRWYPESPKWLFIVQGRKEDARRQLQLLRGYTAGSAALKAEMEEMEQES-- 281
            |.....::.....||  .||||::|.|.:..::.|...||.|    .|:..:..|::||:.||
  Rat   192 LTIIPAILQSAALPF--CPESPRFLLINRKEEDQATEILQRL----WGTPDVIQEIQEMKDESIR 250

  Fly   282 ACEVKTSSLMQVLRDPQLRLPLIIVCAFLGGQQLSGINAIFYYSVSIFRKAGLSSQASEWANLGA 346
            ..:.|..:::::.:.|....||:|.......||.|||||:||||..||:.||:  |...:|.:||
  Rat   251 MSQEKQVTVLELFKSPSYFQPLLISVVLQLSQQFSGINAVFYYSTGIFQDAGV--QEPIYATIGA 313

  Fly   347 GSLNLFASMLGPVLLERVNRRPLMLFSTFFCAVFLLLFAIMLFFIESYSWFGMGCIGCIFLYIFF 411
            |.:|...:::...|:||..||.|.:......||..:...|.|...:.|......||..|.:|:.|
  Rat   314 GVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAVCSVFMTISLLLKDEYEAMSFVCIVAILVYVAF 378

  Fly   412 FQFGLGPMPFFIGAELFELATRPAAMSLGSLAYWLCNFIIGMAFPTMQNLWGALVFLPFS--VTC 474
            |:.|.||:|:||.||||....|||||::...:.|..||::||.||:.....||.||:.|:  :..
  Rat   379 FEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGMFFPSAAAYLGAYVFIIFAAFLVF 443

  Fly   475 LLIFGLTKRYLPETRGR 491
            .|||...|  :|||:||
  Rat   444 FLIFTFFK--VPETKGR 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7882	NP_610189.2	Sugar_tr	43..491	CDD:278511	161/453 (36%)
CG7882	NP_610189.2	MFS	95..480	CDD:119392	139/390 (36%)
Slc2a3	XP_006237357.1	Sugar_tr	15..467	CDD:278511	163/459 (36%)
Slc2a3	XP_006237357.1	MFS	16..450	CDD:119392	157/446 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337762
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	321	0.113	Inparanoid score	I2429
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.800