DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7882 and Y61A9LA.1

DIOPT Version :9

Sequence 1:	NP_610189.2	Gene:	CG7882 / 35520	FlyBaseID:	FBgn0033047	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_504243.2	Gene:	Y61A9LA.1 / 178849	WormBaseID:	WBGene00022014	Length:	526	Species:	Caenorhabditis elegans

Alignment Length:	537	Identity:	139/537 - (25%)
Similarity:	233/537 - (43%)	Gaps:	71/537 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SEAPLMAHENGKQEERPQWSWSLNWAAIGSSLGAAVPVGYCTGVMNSPAELMRSWCNETLIASYD 82
            |:|||:..::. |..|...|.|::..:|...|.:....||...|:|.|...:..:.|.:.|....
Worm    17 SQAPLIEADDA-QRRRVMPSLSIHILSIALCLSSGFQQGYIASVLNQPYAQIEQFINSSWIERTG 80

  Fly    83 LNLSDAGLEILWSAIVSIFLVGGAIGSVVGATMANRFGRRGCFFICGLLLGLGAISFYA---CRP 144
            ..:||:.|.:|||.:...|.:....|..:...|.::|||:....|...|...||:...|   |.|
Worm    81 HPISDSTLHLLWSLLNVCFPIATIFGQFLAGWMCSQFGRKHTALIASFLYIPGALLCAAAKWCFP 145

  Fly   145 LRSVELLLLGRMMVGLAGGLLTSFMSMWHSEISALSQRSTLAPLCPMGLTLGVVIAQVCSLRSVL 209
              :.|||.:||::..||.|:.|...::|..|.:....|..:|.:....:.||.::.|      .:
Worm   146 --AFELLFVGRIIWSLANGVNTVNATVWIVECAPPQIRGRMAAMQEFFMALGSLLTQ------AV 202

  Fly   210 GGP----ENWHFGLAFYGLLVLVCYAPFRWYPESPKWLFIVQGRKEDARRQLQLLRGYTAGSAAL 270
            |.|    |.|.:.......:|:|....|.|..|||:::.......:.||:.|....|.:....::
Worm   203 GVPFSTDELWPYNFLPNCAVVVVSMVMFSWVAESPQFIMEKYNDVDRARKALAQYHGVSEDDPSV 267

  Fly   271 KAEMEEMEQ---ESACEVKTS-------SLMQVL------RDPQLRLPLIIVCA----------- 308
            ::|:...||   ::..:.||:       |.|:::      :|...|  ||..||
Worm   268 ESEIRICEQSIGKNKEKKKTAGGIESEHSGMEIMFMPWRAKDQTSR--LIRYCAWVGVMVKIAYV 330

  Fly   309 FLGGQQLSGINAIFYYSVSIFRKAGLSSQASEWANLGAGSLNLFASMLGPVLLERVNRRPLMLFS 373
            |.|.:.|.|.:....|::|.|    ..|||: |.:...|.|.|..:::...|::|:.||||::.|
Worm   331 FTGARSLRGYSTFILYTLSHF----TYSQAT-WLSFATGLLRLPFTLVPVFLVDRLGRRPLIIVS 390

  Fly   374 TF--FCAVFLLLFAIMLFFIESYSWFGMGCIGCIFLYIFFFQFGLGPMPFFIGAELFELATRPAA 436
            ..  |.::.:::.||.:.....|:.|    ||...| :.....|:|.:..|..|||.......::
Worm   391 MLVSFVSILVMIIAININGELKYATF----IGLTVL-LLVNTCGIGSVSRFYAAELVPRNLLLSS 450

  Fly   437 MSLGSLAYWLCNFIIGMAFPTMQNLWGA---LVFL----PFSVTCLLIFGLTKRYLPETRGRHPS 494
            :|..::...|....:..||....|:.||   |:||    .|:|.|.|:       .|||.....:
Worm   451 VSTLTMFEALTKIGVEFAFYPTANVIGAQSLLLFLIPTGVFTVMCYLM-------CPETSRMTVN 508

  Fly   495 EVAPLVALGFKSKVMLP 511
            ||...||...|..|:.|
Worm   509 EVLNNVAAKKKMDVVFP 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7882	NP_610189.2	Sugar_tr	43..491	CDD:278511	124/490 (25%)
CG7882	NP_610189.2	MFS	95..480	CDD:119392	107/427 (25%)
Y61A9LA.1	NP_504243.2	MFS	42..504	CDD:391944	124/488 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810