DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7882 and R09B5.11

DIOPT Version :9

Sequence 1:	NP_610189.2	Gene:	CG7882 / 35520	FlyBaseID:	FBgn0033047	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_503413.2	Gene:	R09B5.11 / 178634	WormBaseID:	WBGene00019979	Length:	516	Species:	Caenorhabditis elegans

Alignment Length:	507	Identity:	132/507 - (26%)
Similarity:	235/507 - (46%)	Gaps:	29/507 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SLQEQSLTFSEAPLMAHENGKQEERPQWSWSL---NWA-----AIGSSLGAAVPVGYCTGVMNSP 65
            |..:...:||.....:..|.::.|:.....||   ||.     .|.|...|:...|:..|.:|:|
Worm     7 SQNKNDRSFSNMESESSSNVEKSEKENHHQSLPDENWTPFLFFCISSIALASFQDGFQIGCINAP 71

  Fly    66 AELMRSWCNETLIASYDLNLSDAGLEILWSAIVSIFLVGGAIGSVVGATMANRFGRRGCFFICGL 130
            ..|:..|..:.....:...||....:.:||..||:|.|||..||.....:|::|||:.......:
Worm    72 GPLIIDWIKKCHFELFGEVLSQYQADFIWSVAVSMFSVGGMFGSFCSGFLADKFGRKSTLLYNNI 136

  Fly   131 LLGLGAISFYACRPLRSVELLLLGRMMVGLAGGLLTSFMSMWHSEISALSQRSTLAPLCPMGLTL 195
            |..|.|:.....:......:::.||.:|||..|:.:..:.|:.:|::..:.|........:.:::
Worm   137 LALLAAVCLSTSKLFNFYPMIVFGRFLVGLNCGITSGLVPMFLTELAPANLRGKCGSFHQLNISV 201

  Fly   196 GVVIAQVCSLRSVLGGPENWHFGLAFYGLLVLVCYAPFRWYPESPKWLFIVQGRKEDARRQLQLL 260
            .:|::|...|..:.|....|.:..|...:...:..|...:..||||:|......:|:|||.|:.|
Worm   202 AIVLSQALGLPQIFGTQVGWPYIFACVAIPTFLQLATIPFCVESPKYLISKLNDREEARRILEKL 266

  Fly   261 RGYTAGSAALKAEMEEMEQESACEVKTSSLMQVLRDP--------QLRLPLIIVCAFLGGQQLSG 317
            ||:|    .:..|:|.|.||      |...::.|..|        ..:.|:|:....:..||.||
Worm   267 RGHT----KVDEELEHMVQE------TMVTVEPLHQPGYVSLFKGDNQWPMIVSILMMFSQQFSG 321

  Fly   318 INAIFYYSVSIFRKAGLSSQASEWANLGAGSLNLFASMLGPVLLE--RVNRRPLMLFS-TFFCAV 379
            |:|:.:||..||::.|||.....:|.:|.|.:.|.|:.....|::  :..|:.|.:.. :..|..
Worm   322 ISAVTFYSTLIFKRNGLSGNEPMYATVGFGCIKLIATFGCLFLIDHPKFGRKRLHIAGLSGMCIS 386

  Fly   380 FLLLFAIMLFFIESYSWFGMGCIGCIFLYIFFFQFGLGPMPFFIGAELFELATRPAAMSLGSLAY 444
            .:|:...:......|.|.....:..|..::..|.||.||:|:|..:|||:.|||..|.::.:.:.
Worm   387 SILIVITLTLSNAGYHWASYMNVLFILSFVVTFAFGPGPIPWFFTSELFDSATRGRAAAVSATSN 451

  Fly   445 WLCNFIIGMAFPTMQNLWGALVFLPFSVTCLLIFGLTKRYLPETRGRHPSEV 496
            |:.|:::|:.|..:.|:.....||.|:.........|.:::|||:|:.||.:
Worm   452 WVANWMVGLTFLPINNIIHQYAFLMFTFFTFTFAIFTWKFVPETKGKSPSAI 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7882	NP_610189.2	Sugar_tr	43..491	CDD:278511	120/463 (26%)
CG7882	NP_610189.2	MFS	95..480	CDD:119392	104/395 (26%)
R09B5.11	NP_503413.2	Sugar_tr	54..499	CDD:278511	119/454 (26%)
R09B5.11	NP_503413.2	MFS	90..465	CDD:119392	103/384 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I2266
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.870