DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7882 and Slc2a9

DIOPT Version :9

Sequence 1:	NP_610189.2	Gene:	CG7882 / 35520	FlyBaseID:	FBgn0033047	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001095884.1	Gene:	Slc2a9 / 117591	MGIID:	2152844	Length:	538	Species:	Mus musculus

Alignment Length:	513	Identity:	156/513 - (30%)
Similarity:	251/513 - (48%)	Gaps:	36/513 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 APLMAHENG--------KQEERPQWSWSLNWAAIGSSLGAAVPVGYCTGVMNSPAELMRSWCNET 76
            |.||....|        :|....:||:||..||:..:.|::...||...|:|:|...::::.|.|
Mouse     9 ASLMCDTGGPGELSVGHQQRRTKKWSFSLVVAALVGAFGSSFLYGYNLSVVNAPTPYIKAFYNGT 73

  Fly    77 LIASYDLNLSDAGLEILWSAIVSIFLVGGAIGSVVGATMANRFGRRGCFFICGLLLGLG-AIS-- 138
            ....:...:....|.:|||..||||.:||.:|:::...:....||:..     ||:..| |||
Mouse    74 WYRRHGQPIDPDTLTLLWSVTVSIFAIGGLVGTLMVKMIGKFLGRKST-----LLVNNGFAISAA 133

  Fly   139 -FYACRPLR--SVELLLLGRMMVGLAGGLLTSFMSMWHSEISALSQRSTLAPLCPMGLTLGVVIA 200
             ..|| .||  :.|:|::||.::|:.||:..|.:.|:.:|||....|.:|..:..:.:.:||...
Mouse   134 LLMAC-SLRAGTFEMLIVGRFIMGVDGGIALSALPMYLNEISPKEIRGSLGQVTAIFICIGVFSG 197

  Fly   201 QVCSLRSVLGGPENWH--FGLAFYGLLVLVCYAPFRWYPESPKWLFIVQGRKEDARRQLQLLRGY 263
            |:..|..:||....|.  ||:.....||.:...||  .||||::|...:..:..|.:..|..
Mouse   198 QLLGLPELLGRESTWPYLFGVIIVPALVQLASLPF--LPESPRYLLFEKHDEAGAMKAFQTF--- 257

  Fly   264 TAGSAALKAEMEEMEQESACE--VKTSSLMQVLRDPQLRLPLIIVCAFLGGQQLSGINAIFYYSV 326
             .|.|.:..|:||...||..:  ::..|::::||.|.:|..:|.|...:...||.|:|||::|:.
Mouse   258 -LGKADVSQELEEALAESRVQRNLRLVSVLELLRAPFVRWQVITVIITMASYQLCGLNAIWFYTN 321

  Fly   327 SIFRKAGLSSQASEWANLGAGSLNLFASMLGPVLLERVNRRPLMLFSTFFCAVFLLLFAIMLFFI 391
            |||.|||:......:..|..|.:...|::...:::||:.||||::......|:|.......|...
Mouse   322 SIFGKAGIPQDKIPYITLSTGGIETLAAIFSGLVIERLGRRPLLIGGFGLMALFFGTLTATLTLQ 386

  Fly   392 ESYSWFGMGCIGCIFLYIFFFQFGLGPMPFFIGAELFELATRPAAMSLGSLAYWLCNFIIGMAFP 456
            :...|.....|.||...|..|..|.|.:||.:..|.|:.:.||||..:.....||.||.:|:.||
Mouse   387 DQAPWVPYLSIVCILAIIASFCSGPGGIPFILTGEFFQQSERPAAFMIAGTVNWLSNFAVGLLFP 451

  Fly   457 TMQNLWGALVFLPFSVTCLLIFGLTKRY--LPETRGRHPSEVAPLVALGFKSKVMLPK 512
            .:|....:..||.|:..|  |.|.|..|  ||||:.|..:|::.  |...::|...|:
Mouse   452 FIQKSLDSYCFLVFATIC--IAGATYFYFVLPETKNRTHAEISQ--AFAKRNKAQPPE 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7882	NP_610189.2	Sugar_tr	43..491	CDD:278511	142/459 (31%)
CG7882	NP_610189.2	MFS	95..480	CDD:119392	122/394 (31%)
Slc2a9	NP_001095884.1	MFS_GLUT_Class2	40..491	CDD:340990	143/464 (31%)
Slc2a9	NP_001095884.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	495..538		2/11 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834434
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0569
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	320	1.000	Inparanoid score	I2506
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D291809at33208
OrthoFinder	1	1.000	-	-		FOG0000120
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.800