DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7882 and slc22a2

DIOPT Version :9

Sequence 1:	NP_610189.2	Gene:	CG7882 / 35520	FlyBaseID:	FBgn0033047	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	XP_002933908.1	Gene:	slc22a2 / 100487774	XenbaseID:	XB-GENE-965056	Length:	544	Species:	Xenopus tropicalis

Alignment Length:	554	Identity:	119/554 - (21%)
Similarity:	204/554 - (36%)	Gaps:	186/554 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 GKQEERPQWSWSLNWAAIGSSLGAAVPVGYCTGVMNSPAELMRSWCNETLIASYD-------LNL 85
            |..|...:..|:||:                ||...|...|..|.|.:     ||       ||.
Frog    54 GIPEPSNECEWTLNY----------------TGPNGSTDSLYMSQCYQ-----YDVDWNSTSLNC 97

  Fly    86 SDAGLEIL-----------W------SAIVSIF-----------------LVGGAIGSVVGATMA 116
            :::.|.|.           |      |::|:.|                 .:|..||.::...:|
Frog    98 TNSSLNITSKLPITNCKDGWDYNTTGSSLVTEFNLVCGDSWKLDFFQSCVNIGFFIGGLISGYIA 162

  Fly   117 NRFGRRGCFFICGLLL-GLGAI--SFYACRPLRSVELLLLGRMMVG--LAGGLLTSFMSMWHSEI 176
            :||||:. |.|..:|: |:..|  :|....||......:.|.:..|  |:|.:|.       :|.
Frog   163 DRFGRKP-FLISSILITGIFGILMAFAPNYPLVVTFRFIQGFVSKGCWLSGYILV-------AEF 219

  Fly   177 SALSQRSTLAPLCPMGLTLGVVIAQVCSLRSVLGGPENWH-----------FGLAFYGLLVLVCY 230
            ..|..|.|:..:.....|:|:::     |..|.....:|.           |.||:|
Frog   220 VGLEHRRTVGIVYQAAFTVGLLL-----LSGVAYVLPHWRWLQMTVTIPYFFFLAYY-------- 271

  Fly   231 APFRW-YPESPKWLFIVQGRKEDARRQLQLLRGYTAGSAALKAEMEEME----QESACEVKTSSL 290
                | .||||:|| |.|.||.:|:..:     :|......|...:.:|    .|.|.|.:..|.
Frog   272 ----WCVPESPRWL-ISQNRKAEAKAII-----HTIAKKNGKMVPDFLESLTADEEAGEKQVPSF 326

  Fly   291 MQVLRDPQLRLPLIIV------CAFLGGQQLSGINAIFYYSVSIFRKAGLSSQASEWANLGAGSL 349
            :.::|.||:|...:|:      ||.:             |..||.             ::|:.:.
Frog   327 LDLVRTPQIRKHTLILMYIWFTCAVV-------------YQGSIM-------------HMGSTAE 365

  Fly   350 NLF------------ASMLGPVLLERVNRRPLMLFSTFFCAVFLLLFAIMLFFI-ESYSW--FGM 399
            |::            :::|..|.::||.||    :....|.:...:..::..|| ..|||  ..:
Frog   366 NIYFDFFISALVEFPSAILIIVTVDRVGRR----YPWLVCCIITGITCLITAFIPHGYSWLIITL 426

  Fly   400 GCIGCIFLYIFFFQFGLGPMPFFIGAELFELATRPAAMSLGSLAYWLCNFII---GMAFP----T 457
            .|:..:.:.:.:      .|...:.|||:....|       :|...:|:.:.   |:..|    .
Frog   427 SCVSRMGITVSY------EMVCLVNAELYPTFIR-------NLGIMVCSSMCDLGGVITPFIVYR 478

  Fly   458 MQNLWGALVFLPFSVTCLLIFGLTKRYLPETRGR 491
            :..:|..|..:.|:|.. .:.|:...:||||:||
Frog   479 LAAIWQELPLIVFAVLA-TVSGILVYFLPETKGR 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7882	NP_610189.2	Sugar_tr	43..491	CDD:278511	112/537 (21%)
CG7882	NP_610189.2	MFS	95..480	CDD:119392	94/450 (21%)
slc22a2	XP_002933908.1	2A0119	12..516	CDD:273328	119/554 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D326501at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010