Protein Alignment CG43366 and Serpina12

DIOPT Version :9

• Sequence 1: NP_610188.2
• Gene: CG43366 / 35519
• FlyBaseID: FBgn0263109
• Length: 2140
• Species: Drosophila melanogaster
• Sequence 2: NP_080811.1
• Gene: Serpina12 / 68054
• MGIID: 1915304
• Length: 413
• Species: Mus musculus
• Alignment Length: 480
• Identity: 93/480 - (19%)
• Similarity: 184/480 - (38%)
• Gaps: 131/480 - (27%)

  Fly  1677 EDLQSFARLCNELAFSYWRAITSEKISSARSLVISPFALTSMLSMVFLGARGSTSGEMNEILKLD 1741
            :|.:..||...|..|...:.:.|.  |...::.:||.::::..||:.|||:.||..|:.|.....
Mouse    43 KDARQLARHNMEFGFKLLQRLASN--SPQGNIFLSPLSISTAFSMLSLGAQNSTLEEIREGFNFK 105

  Fly  1742 DMVTFNPHLIFKNITNSVEQASDS---DIATAAFVREIFSDRANGKILP--FFKEKTQQLYAGHV 1801
            :|..::.|..|..:.:.:.|.::.   ::..|.|:.:        |:.|  .|....:.:|...:
Mouse   106 EMSNWDVHAAFHYLLHKLNQETEDTKMNLGNALFMDQ--------KLRPQQRFLNLAKNVYDADM 162

  Fly  1802 EEVNFH-------VVNDIVRRRTNL----LVKRHTMGKVLEYLRTNSVWVNGPLATISANLFQTD 1855
            ...||.       .:|..:.::|:.    :||....|.|:  :.||.::..|        .:|.:
Mouse   163 VLTNFQDLENTQKDINRYISQKTHSRIKNMVKSIDPGTVM--ILTNYIYFRG--------RWQYE 217

  Fly  1856 CSHGSTTDRDGEMFFQVHPTVRQRRLVPIPAVLYRSGFLAGYEPSLDATVVSFGRVQNTVSTVYV 1920
            .....|.:   |.||     :.:.:.|.:|.:..|..:...|:..|..|::.. ..:..::..:|
Mouse   218 FDPKQTKE---EEFF-----IEKGKTVKVPMMFQRGLYDMAYDSQLSCTILEI-PYRGNITATFV 273

  Fly  1921 MPGHQSSISPMDN--LDRLERSLVETAFSDKQAWRRLLTSLMDRPGMEVQLPRFSHRSFVNASLG 1983
            :|         ||  |..||:.|....|:   .|:    ||:.:..::|.:|:....|..|....
Mouse   274 LP---------DNGKLKLLEQGLQADIFA---KWK----SLLSKRVVDVWVPKLRISSTYNMKKV 322

  Fly  1984 LQKMGLRGLFKSDFADLRGLTGAGNRDIFLSDMIQINTFSTCGEEKISEHHHVEMYPAPPLRKRN 2048
            |.::|:..:|:.            |.|:                .:||.|..:::
Mouse   323 LSRLGISKIFEE------------NGDL----------------TRISSHRSLKV---------- 349

  Fly  2049 KDVDATDDDAFDSSERVVDFGSLVQESALGRGFYDDLLDPKYLELPLPLRPRQARVPDAPR-LRF 2112
                   .:|...:|..:|...:  |.|.|.|           ...||:        :.|| ::.
Mouse   350 -------GEAVHKAELKMDEKGM--EGAAGSG-----------AQTLPM--------ETPRHMKL 386

  Fly  2113 DKPFLYFVRHNPTGMILFMGR-FNP 2136
            |:|||..:..|....::|:.| ::|
Mouse   387 DRPFLMMIYENFMPSMVFLARIYDP 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43366	NP_610188.2	SERPIN	1687..2136	CDD:294093	89/468 (19%)
Serpina12	NP_080811.1	alpha-1-antitrypsin_like	51..408	CDD:239011	88/467 (19%)
		Reactive center loop. /evidence=ECO:0000250|UniProtKB:Q8IW75	364..382		6/38 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100