Protein Alignment CG43366 and SERPINA4

DIOPT Version :9

• Sequence 1: NP_610188.2
• Gene: CG43366 / 35519
• FlyBaseID: FBgn0263109
• Length: 2140
• Species: Drosophila melanogaster
• Sequence 2: NP_001275961.1
• Gene: SERPINA4 / 5267
• HGNCID: 8948
• Length: 464
• Species: Homo sapiens
• Alignment Length: 545
• Identity: 104/545 - (19%)
• Similarity: 196/545 - (35%)
• Gaps: 185/545 - (33%)

  Fly  1640 LLINLMASS-----------TQSTRPPVKLDPSPESSQGLEASTAMMDEDLQSFARLCNELAFSY 1693
            ||:.|:|.|           :.|.....::..:.|.|..|:.:.|..|            .||.:
Human    47 LLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANAD------------FAFRF 99

  Fly  1694 WRAITSEKISSARSLVISPFALTSMLSMVFLGARGSTSGEMNEIL--KLDDMVTFNPHLIFKNIT 1756
            :..|.||  :..:::..||.::::..:|:.|||...:..::.|.|  .|.::...:.|..|:::.
Human   100 YYLIASE--TPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLL 162

  Fly  1757 NSVE---QASDSDIATAAFVREIFSDRANGKILPFFKEKTQQLYAGHVEEVNFH-------VVND 1811
            :::.   ...::.:.:|.|:..      |.|.|..|...|..:|...:...||:       ::||
Human   163 HTLNLPGHGLETRVGSALFLSH------NLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLIND 221

  Fly  1812 IVRRRT-----NLL--VKRHTMGKVLEYLRTNSVWVNGPLATISANLFQTDCSHGSTTDRDGEMF 1869
            .|::.|     :|:  :|:..:..::.|:...::|....:::             .||.:|  .:
Human   222 HVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISS-------------RTTPKD--FY 271

  Fly  1870 FQVHPTVRQRRLVP----------------IPAVLYRSGFLAGYEPSLDATVVSFGRVQNTVSTV 1918
            ...:.|||    ||                :|..:.|..:..      ||||            .
Human   272 VDENTTVR----VPMMLQDQEHHWYLHDRYLPCSVLRMDYKG------DATV------------F 314

  Fly  1919 YVMP--GHQSSISPMDNLDRLERSLVETAFSDKQAWRRLLTSLMDRPGMEVQLPRFS-HRSFVNA 1980
            :::|  |....|..:...:.|.|            |..||........:|:.||:|| ..|:|..
Human   315 FILPNQGKMREIEEVLTPEMLMR------------WNNLLRKRNFYKKLELHLPKFSISGSYVLD 367

  Fly  1981 SLGLQKMGLRGLFKSDFADLRGLTGAGNRDIFLSDMIQINTFSTCGEEKI--SEHHHVEMYPAPP 2043
            .: |.::|...|| |.:|||.|:|                     .::|:  |:..|
Human   368 QI-LPRLGFTDLF-SKWADLSGIT---------------------KQQKLEASKSFH-------- 401

  Fly  2044 LRKRNKDVDATDDDAFDSSERVVDFGSLVQESALGRGFYDDLLDPKYLELPLPLRPRQARVPDAP 2108
              |...|||....:|..::...:.|.|......:
Human   402 --KATLDVDEAGTEAAAATSFAIKFFSAQTNRHI------------------------------- 433

  Fly  2109 RLRFDKPFLYFVRHNPTGMILFMGR 2133
             |||::|||..:....|..:||:|:
Human   434 -LRFNRPFLVVIFSTSTQSVLFLGK 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43366	NP_610188.2	SERPIN	1687..2136	CDD:294093	93/487 (19%)
SERPINA4	NP_001275961.1	alpha-1-antitrypsin_like	91..458	CDD:239011	95/501 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100