Protein Alignment CG43366 and SERPINE1

DIOPT Version :9

• Sequence 1: NP_610188.2
• Gene: CG43366 / 35519
• FlyBaseID: FBgn0263109
• Length: 2140
• Species: Drosophila melanogaster
• Sequence 2: NP_001373389.1
• Gene: SERPINE1 / 5054
• HGNCID: 8583
• Length: 492
• Species: Homo sapiens
• Alignment Length: 485
• Identity: 107/485 - (22%)
• Similarity: 178/485 - (36%)
• Gaps: 166/485 - (34%)

  Fly  1683 ARLCNELAFSYWRAITSEKISSARSLVISPFALTSMLSMVFLGARGSTSGEMNEIL--KLDD--M 1743
            |.|.::.....::.:.  :.|..|::|.||:.:.|:|:|:.|...|.|..::...:  |:||  |
Human    32 AHLASDFGVRVFQQVA--QASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGM 94

  Fly  1744 VTFNPHLIFKNITN--SVEQASDSDIATAAFV-REIFSDRANGKILPFFKEKTQQLYAGHVEEVN 1805
            .....|| :|.:..  :.::.|.:|   |.|| |::       |::..|.....:|:...|::|:
Human    95 APALRHL-YKELMGPWNKDEISTTD---AIFVQRDL-------KLVQGFMPHFFRLFRSTVKQVD 148

  Fly  1806 F-------HVVNDIVRRRT-----NLLVKRHTMGKVLEYLR---TNSVWVNG------PLATISA 1849
            |       .::||.|:..|     |||.|    |.|.:..|   .|:::.||      |.::...
Human   149 FSEVERARFIINDWVKTHTKGMISNLLGK----GAVDQLTRLVLVNALYFNGQWKTPFPDSSTHR 209

  Fly  1850 NLFQTDCSHGSTTDRDGEMFFQVHPTVRQRRLVPIPAVLYRSGFLAGYEPSLDATVVSFGRVQNT 1914
            .||..  |.|||                    |.:|.:...:.|          ....|......
Human   210 RLFHK--SDGST--------------------VSVPMMAQTNKF----------NYTEFTTPDGH 242

  Fly  1915 VSTVYVMPGHQSSIS-----------PMDNLDR-LERSLVETAFSDKQAWRRLLTSLMDRPGMEV 1967
            ...:..:|.|..::|           |:..|.. |...|:       ..|:..:|.|   |.:.|
Human   243 YYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLI-------SHWKGNMTRL---PRLLV 297

  Fly  1968 QLPRFSHRSFVNASLGLQKMGLRGLFKSDFADLRGLTGAGNRDIFLSDMIQINTFSTCGEEKISE 2032
             ||:||..:.|:....|:.:|:..:|:...||...          |||               .|
Human   298 -LPKFSLETEVDLRKPLENLGMTDMFRQFQADFTS----------LSD---------------QE 336

  Fly  2033 HHHVEMYPAPPLRKRNKDVDATDDDAFDSSERVVDFGSLVQESALGRGFYDDLLDPKYLELPLPL 2097
            ..||    |..|:|...:|:.:...|..|:..:|
Human   337 PLHV----AQALQKVKIEVNESGTVASSSTAVIV------------------------------- 366

  Fly  2098 RPRQARVPDAP-RLRFDKPFLYFVRHNPTG 2126
               .||:  || .:..|:|||:.|||||||
Human   367 ---SARM--APEEIIMDRPFLFVVRHNPTG 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43366	NP_610188.2	SERPIN	1687..2136	CDD:294093	105/481 (22%)
SERPINE1	NP_001373389.1	serpinE1_PAI-1	29..393	CDD:381007	107/485 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100