Protein Alignment CG43366 and serpina3

DIOPT Version :10

• Sequence 1: NP_610188.2
• Gene: CG43366 / 35519
• FlyBaseID: FBgn0263109
• Length: 2140
• Species: Drosophila melanogaster
• Sequence 2: NP_001011275.1
• Gene: serpina3 / 496728
• XenbaseID: XB-GENE-5933441
• Length: 414
• Species: Xenopus tropicalis
• Alignment Length: 349
• Identity: 76/349 - (21%)
• Similarity: 136/349 - (38%)
• Gaps: 86/349 - (24%)

  Fly  1699 SEKISSARSLVISPFALTSMLSMVFLGARGSTSGEMNEILKL-------DDMVTFNPHLIFKNIT 1756
            :||.|:.:::|.||.::.:..||:.|||:..:..::...|.|       :||.....||:  .:.
 Frog    61 AEKESTQKNIVFSPLSILTAFSMLLLGAKSESHQQILSGLSLNQTQVPEEDMHEAFEHLL--QVL 123

  Fly  1757 NSVEQASDSDIATAAFVREIFSDRANGKILPFFKEKTQQLYAGHVEEVNFHV---------VNDI 1812
            |..:......|..|.||.:..      |||..|.::.:..|  |.|....|.         :||.
 Frog   124 NRPKSDLQVKIGNAVFVEDTL------KILDSFVQEIEHHY--HAEIFPSHFKNPAEAEKQINDF 180

  Fly  1813 VRRRT----NLLVK---RHTMGKVLEYLRTNSVWVNGPLATISANLFQTDCSHGSTTD------R 1864
            |..:|    ..|||   ..|...|:.::..|:.|.| |.::...:..|......:|.:      .
 Frog   181 VNNKTEGRIQELVKDLSEATKLVVINFILFNAEWQN-PFSSFFTHSRQFSVDENTTVEVQMMSKT 244

  Fly  1865 DGEMFFQVHPTVRQRRLVPIPAVLYRSGFLAGYEPSLDATVVSFGRVQNTVSTVYVMPGHQSSIS 1929
            |...|::                          :..:..:|:.. ..:|..|.:.::|
 Frog   245 DLYQFYK--------------------------DEKIPCSVLQL-PYKNNASMLIIVP------- 275

  Fly  1930 PMDNLDRLERSL-VETAFSDKQAWRRLLTSLMDRPGMEVQLPRFSHRSFVNASLGLQKMGLRGLF 1993
            .:..:..:|.:| |||.    :.|    ||..::...|:.||:||..|.:.....|..||: |:.
 Frog   276 ELGKIHEVEEALSVETL----KRW----TSSAEKSFFELFLPKFSISSSLKLKDILTDMGM-GII 331

  Fly  1994 KSDFADLRGLTGAGNRDIFLSDMI 2017
            .:|.||..|:  :.|..:.||.::
 Frog   332 FTDAADFSGI--SENSRLKLSKVV 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43366	NP_610188.2	MDN1	956..>1505	CDD:444083
		Serpin	1687..2136	CDD:459662	76/349 (22%)
serpina3	NP_001011275.1	serpinA	43..411	CDD:381073	76/349 (22%)