DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG43366 and Serpina11

DIOPT Version :9

Sequence 1:	NP_610188.2	Gene:	CG43366 / 35519	FlyBaseID:	FBgn0263109	Length:	2140	Species:	Drosophila melanogaster
Sequence 2:	NP_955018.2	Gene:	Serpina11 / 380780	MGIID:	2685741	Length:	427	Species:	Mus musculus

Alignment Length:	522	Identity:	115/522 - (22%)
Similarity:	190/522 - (36%)	Gaps:	158/522 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly  1655 PVKLDP------------SPESSQGLEASTA--MMDEDLQSFA-RLCNELAFSYWRAITSEKISS 1704
            ||...|            .|.|.|.||.:.|  .:...:.:|| ||..:||         |::
Mouse    21 PVHCQPFSAHGDKSLGASQPASHQSLEPAPAYHKVTPTITNFALRLYKQLA---------EEV-- 74

  Fly  1705 ARSLVISPFALTSMLSMVFLGARGSTSGEMNEIL--KLDDMVTFNPHLIFKNITNSVEQASDS-D 1766
            |.:::.||.:|:|.|:::.|||...|..::.|.|  .|.:....:.|..|:::.::::..|.. :
Mouse    75 AGNILFSPVSLSSSLALLSLGAHADTQTQILESLGFNLTETPAADVHRGFQSLLHTLDLPSPKLE 139

  Fly  1767 IATAAFVREIFSDRANGKILP--FFKEKTQQLYAGHVEEVNF-------HVVNDIVRRRTNLLV- 1821
            :....|   :|.||   ::.|  .|.:..::||.......||       ..:||:||::|...|
Mouse   140 LKLGHF---LFLDR---QLKPQQRFLDSAKELYGALAFSANFTEAAATGQQINDLVRKQTYGQVV 198

  Fly  1822 ------KRHTMGKVLEYLRTNSVWVNGPLATISANLFQTDCSH--GSTTDRDGEMFFQVHPTVRQ 1878
                  ...|:..:|.|:                 .|:..|.|  .....|..|.|     ::.|
Mouse   199 GCLPEFSHDTLMVLLNYI-----------------FFKAKCKHPFDRYQTRKQESF-----SLDQ 241

  Fly  1879 RRLVPIPAVLYRSGFLAGYEPSLDATVVSFGRVQNTVSTVYVMPGHQSSISPMDNLDRLERSLVE 1943
            |..:.||.:..:......|:.....||:.. ....|...:.|:|            |..:...||
Mouse   242 RTPLRIPMMRQKEMHRFLYDQEASCTVLQI-EYSGTALLLLVLP------------DPGKMQQVE 293

  Fly  1944 TAFSDK--QAW-RRLLTSLMDRPGMEVQLPRFSHRSFVNASLGLQKMGLRGLFKSDFADLRGLTG 2005
            .|...:  :.| :|.|.||:|     :.|||||..:..|....|..:||..||..: |||.|:.|
Mouse   294 AALQPETLRRWGQRFLPSLLD-----LHLPRFSISATYNLEEILPLIGLGNLFDME-ADLSGIMG 352

  Fly  2006 AGNRDIFLSDMIQINTFSTCGEEKISEHHHVEMYPAPPLRKRNKDVDATDDDAFDSSERVVDFGS 2070
                                                    :.||.|...      |.:.:||...
Mouse   353 ----------------------------------------QLNKTVSRV------SHKAIVDMNE 371

  Fly  2071 LVQESALGRGFYDDLLDPKYLELPLPLRPRQARVPDAPRLRFDKPFLYFVRHNPTGMILFMGR-F 2134
            ...|:|...|              |..:|....:..||:..:::|||..:....|..:||:|: .
Mouse   372 KGTEAAAASG--------------LLSQPPALNMTSAPQAHYNRPFLLLLWEVTTQSLLFLGKVV 422

  Fly  2135 NP 2136
            ||
Mouse   423 NP 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43366	NP_610188.2	SERPIN	1687..2136	CDD:294093	100/473 (21%)
Serpina11	NP_955018.2	SERPIN	58..421	CDD:294093	104/480 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100