DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43366 and Serpinb1b

DIOPT Version :9

Sequence 1:	NP_610188.2	Gene:	CG43366 / 35519	FlyBaseID:	FBgn0263109	Length:	2140	Species:	Drosophila melanogaster
Sequence 2:	XP_038952280.1	Gene:	Serpinb1b / 306891	RGDID:	1560658	Length:	380	Species:	Rattus norvegicus

Alignment Length:	466	Identity:	110/466 - (23%)
Similarity:	187/466 - (40%)	Gaps:	123/466 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly  1700 EKISSARSL-----------------VISPFALTSMLSMVFLGARGSTSGEMNEILKLDDMVTFN 1747
            |::|||.||                 :.|||:::|.|:||||||:||::...   |:|.:...|:
  Rat     2 EQLSSANSLFALELFHTLSESSPTGNIFSPFSISSALAMVFLGAKGSSAPSS---LRLAETFHFD 63

  Fly  1748 P----HLIFKNITNSVEQASDSDIATAAFVREIFSDRANGKILPFFKEKTQQLYAGHVEEVNFHV 1808
            .    |..|:::...:.:...|.  |......::.::.. ..||.|...||::|...:..|:|..
  Rat    64 SVEDIHSRFQSLNAEMRKHGASH--TLKVANRLYGEKTY-NFLPEFLASTQKMYGADLAPVDFQH 125

  Fly  1809 VNDIVRRRTNLLVKRHTMGKVLEYLRTNSVWVNGPLATISANLFQTDCSHGSTTDRDG---EMFF 1870
            .::..|:..|..||..|.||:.|.|....|.....|..::|..|:            |   |.|.
  Rat   126 ASEDARKEINKWVKGQTEGKIPELLAGGVVNSTTKLVLVNAIYFK------------GIWQEKFL 178

  Fly  1871 QVHPTVRQRRL----VPIPAVLY-RSGFLAGYEPSLDATVVSFGRVQNTVSTVYVMPGHQSSISP 1930
            ..|.|....||    ..:..::| :..|..||.|.|...|:........:|.|.::|  :.....
  Rat   179 TRHTTDAPFRLNKKDTKMVKMMYQKEKFPFGYIPDLKCKVLEMPYQGGELSMVILLP--EDIEDE 241

  Fly  1931 MDNLDRLERSL-VETAFSDKQAWRRLLTSLMDRPGMEVQLPRFS-HRSFV-NASLGLQKMGLRGL 1992
            ...|.::|..| :|..:.    |.:  ...:....:.|.||:|. ..|:: |::||  ::||:.|
  Rat   242 STGLQKIEEQLTLEKLYE----WTK--HENLKEIDVHVNLPKFKIEESYILNSNLG--RLGLQDL 298

  Fly  1993 FKSDFADLRGLTGAGNRDIFLSDMIQINTFSTCGEEKISEHHHVEMYPAPPLRKRNKDVDATDDD 2057
            |.|..|||.|:  :.:||||:|.::                           .|...:|:....:
  Rat   299 FSSSKADLSGM--SESRDIFISKIV---------------------------HKSFVEVNEEGTE 334

  Fly  2058 AFDSSERVVDFGSLVQESALGRGFYDDLLDPKYLELPLPLRPRQARVPDAPRLRFDKPFLYFVRH 2122
            |..::..:|::..:..|:.:                                  .|.|||:|:||
  Rat   335 AAAATAGLVEYCLVSIEAFI----------------------------------VDHPFLFFIRH 365

  Fly  2123 NPTGMILFMGR 2133
            |||..:||.||
  Rat   366 NPTANMLFFGR 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43366	NP_610188.2	SERPIN	1687..2136	CDD:294093	110/466 (24%)
Serpinb1b	XP_038952280.1	serpinB1_LEI	1..380	CDD:381028	110/466 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100