Protein Alignment CG43366 and SERPIND1

DIOPT Version :9

• Sequence 1: NP_610188.2
• Gene: CG43366 / 35519
• FlyBaseID: FBgn0263109
• Length: 2140
• Species: Drosophila melanogaster
• Sequence 2: NP_000176.2
• Gene: SERPIND1 / 3053
• HGNCID: 4838
• Length: 499
• Species: Homo sapiens
• Alignment Length: 469
• Identity: 93/469 - (19%)
• Similarity: 179/469 - (38%)
• Gaps: 124/469 - (26%)

  Fly  1688 ELAFSYWRAITSEKISSARSLVISPFALTSMLSMVFLGARGSTSGEMNEILKLDDMVTFNP---- 1748
            :.||:.:| :..:::::..::.|:|..:::.:.|:.||.:|.|..:::.||...|.|..:.
Human   132 KFAFNLYR-VLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNASSKYEI 195

  Fly  1749 ---HLIFKNITNSVEQASDSDIATAAFVREIFSDRANGKILPFFKEKTQQLYAGHVEEVNFHVVN 1810
               |.:|:.:|:.:.:.:..  .|...|.:::..: ...||..||.|.::.|....:..:|.  :
Human   196 TTIHNLFRKLTHRLFRRNFG--YTLRSVNDLYIQK-QFPILLDFKTKVREYYFAEAQIADFS--D 255

  Fly  1811 DIVRRRTNLLVKRHTMGKVLEYLRT----------NSVWVNGPLATISANLFQTDCSHGSTTDRD 1865
            .....:||..:.:.|.|.:.:.|..          |.::..|..    .|.|..:.:|...
Human   256 PAFISKTNNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSW----VNKFPVEMTHNHN---- 312

  Fly  1866 GEMFFQVHPTVRQRRLVPIPAVLYRSGFLAGYEPSLDATVVSFGRVQNTVSTVYVMPGHQSSISP 1930
                |:::    :|.:|.:..:..:..|||..:..||..::....| ..:|.:.|:| |:
Human   313 ----FRLN----EREVVKVSMMQTKGNFLAANDQELDCDILQLEYV-GGISMLIVVP-HK----- 362

  Fly  1931 MDNLDRLERSLVETAFSDKQAWRRLLTSLMDRPGMEVQLPRFSHRSFVNASLGLQKMGLRGLFKS 1995
            |..:..||..|.....   :.|::.:|:..    .||.||:|......|....|:.||:|.||..
Human   363 MSGMKTLEAQLTPRVV---ERWQKSMTNRT----REVLLPKFKLEKNYNLVESLKLMGIRMLFDK 420

  Fly  1996 DFADLRGLTGAGNRDIFLSDMIQINTFSTCGEEKISEHHHVEMYPAPPLRKRNKDVDATDDDAFD 2060
            :          ||........|.|:.|...|...::|                :...||
Human   421 N----------GNMAGISDQRIAIDLFKHQGTITVNE----------------EGTQAT------ 453

  Fly  2061 SSERVVDFGSLVQESALGRGFYDDLLDPKYLELPLPLRPRQARVPDAPRLRF--DKPFLYFVRHN 2123
                          :....||                      :|.:.::||  |:|||:.:..:
Human   454 --------------TVTTVGF----------------------MPLSTQVRFTVDRPFLFLIYEH 482

  Fly  2124 PTGMILFMGRF-NP 2136
            .|..:|||||. ||
Human   483 RTSCLLFMGRVANP 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43366	NP_610188.2	SERPIN	1687..2136	CDD:294093	91/467 (19%)
SERPIND1	NP_000176.2	HCII	62..497	CDD:239002	93/469 (20%)
		Chemotactic activity	68..79
		2 X 11 AA approximate repeats, Asp/Glu-rich (acidic) (hirudin-like)	73..97
		Glycosaminoglycan-binding site	192..212		3/19 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100